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Request The Product List ofPDK1 PDK1

Cat. No. Product Name Information
PC-49261

GSK2334470

PDK1 inhibitor

GSK2334470 (GSK 2334470) is a potent, highly specific inhibitor of PDK1 with IC50 of 10 nM, does not inhibit 93 other protein kinases including 13 AGC-kinases most related to PDK1 at 5 uM.
PC-62481

PS 210

PS 210 is a potent, specific activator of PDK1 that target the PIF-binding pocket of PDK1, does not alter the activity of any of the 121 kinases (S6K, PKB/Akt or GSK3)..
PC-60606

OSU-03013

OSU-03013 (OSU 03013, OSU03013) is a novel potent, orally active 3-phosphoinositide-dependent kinase-1 (PDK-1) with IC50 of 2 uM.
PC-60605

OSU-03012

OSU-03012 (AR-12) is a novel potent, orally active 3-phosphoinositide-dependent kinase-1 (PDK-1) with IC50 of 5 uM.
PC-42781

BX-912

BX-912 (BX912) is a potent, selective and ATP-competitive inhibitor of PDK1 with IC50 of 26 nM.
PC-42629

BX795

PDK1 inhibitor

BX795 is a potent and relatively specific PDK1 inhibitor with IC50 of 6 nM.
PC-21484

CU05-1189

PDK1 inhibitor

CU05-1189 is a non-peptide, allosteric inhibitor of the pleckstrin homology (PH) domain of PDK1, specifically inhibits Akt signaling pathway.
PC-73258

PDK-1 agonist PS48

PDK-1 agonist

PDK-1 agonist PS48 is a small molecule allosteric PDK-1 agonist, PS48 is active at 10 nM to 1 μM in restoring normal insulin-dependent Akt activation and in mitigating Aβi peptide toxicity.
PC-63030

BX-320

BX-320 is a potent, selective and ATP-competitive inhibitor of PDK1 with IC50 of 30 nM, >20-fold selectivity over PKA.
PC-62480

PS 423

PS 423 is a substrate-selective inhibitor of PDK1, inhibits the phosphorylation and activation of S6K without affecting the PKB/Akt signaling pathway in HEK293 cells, the prodrug of PS210.
PC-61111

PDK1 inhibitor 7

A potent, selective PDK1 inhibitor with IC50 of 1 nM, displays >3,000-fold selectivity against a panel of 256 kinases.

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