| Cat. No. |
Product Name |
Information |
| PC-49253 |
MBX-102 acid
PPARγ agonist
|
MBX-102 acid is the active form of JNJ39659100 (MBX-102), a selective partial PPAR-γ agonist with EC50 of 23.34 uM (hPPAR-γ), enhances insulin sensitivity in vitro in 3T3-L1 adipocytes, binds to the PPAR-γ LBD in a manner that is distinct from but overlapping with rosiglitazone. |
| PC-49252 |
JNJ39659100
PPARγ agonist
|
JNJ39659100 (MBX-102) is a nonthiazolidinedione (TZD) selective partial PPAR-γ agonist with insulin-sensitizing and glucose-lowering properties comparable to TZDs without dose-dependent increases in body weight, the prodrug ester of MBX-102 acid. |
| PC-38677 |
Ibrigampar
PPARγ modulator
|
Ibrigampar (AMG131, INT131, CHS131) is a selective, orally active PPARγ modulator (partial agonist) with binding IC50 of 17 nM, and PPARγ transactivation EC50 of 150 nM, enhances insulin sensitivity. |
| PC-38650 |
MMT-160
PPARγ inhibitor
|
MMT-160 is a novel selective peroxisome proliferator-activated receptor γ (PPARγ) antagonist with IC50 of 0.17 uM, covalently binds to the PPARγ ligand binding domain (LBD) via Cys285. |
| PC-72656 |
NXT629
PPARα antagonist
|
NXT629 (NXT-629) is a potent, selective PPARα antagonist with IC50 of 78 nM, no effect against PPARδ and PPARγ (IC50>30 uM). |
| PC-72023 |
FK614
PPARγ agonist
|
FK614 (FK 614) is a PPARγ agonist. |
| PC-35942 |
BR101549
|
BR101549 (BR-101549) is a novel PPARγ non-TZD agonist with EC50 of 1.73 uM (Amax 120%).. |
| PC-35702 |
MA-0204
|
MA-0204 (MA0204) is a potent, selective PPARδ modulator with EC50 of 0.4 nM (human PPARδ), dispalys no activity (10,000-fold selectivity) against PPARα and PPARγ. |
| PC-35674 |
DS-6930
|
DS-6930 (DS 6930, DS6930) is a novel potent, selective PPARγ agonist with EC50 of 41 nM, Emax-68%. |
| PC-35669 |
DS-6930b
|
DS-6930b (DS-6930 calcium salt) is the calcium salt of DS-6930, which is a novel potent, selective PPARγ agonist with EC50 of 41 nM, Emax-68%. |
| PC-35555 |
Fonadelpar
|
Fonadelpar (NPS-005,SJP-0035) is a potent, selective peroxisome proliferator activated receptor δ (PPARδ) agonist for the treatment of corneal disorders.. |
| PC-35153 |
PPARα activator compound 3
|
PPARα activator compound 3 is a specific PPAR activator that selectively up-regulates PPARα transcriptional activity, leading to PPARα target gene expression both in vitro and in vivo. |
