| Cat. No. |
Product Name |
Information |
| PC-43009 |
GSK0660
|
GSK0660 is a potent, selective, dual PPARβ/δ antagonist with pIC50 of 6.8 (160 nM), shows no activity on PPARα and PPARγ (IC50>10 uM). |
| PC-63148 |
AZD 6610
|
AZD 6610 is a dual peroxisome proliferator-activated receptor (PPAR) α/γ agonist for treatment of diabetes mellitus.. |
| PC-62445 |
GW-7647
|
GW-7647 is a potent, selective PPARα agonist with EC50 of 6 nM, dispalys high selectivity over PPARγ and PPARδ. |
| PC-62431 |
MCC 555
|
MCC 555 (Isaglitazone. |
| PC-62345 |
MRL20
|
MRL20 is a novel synthetic PPARγ ligand and orthosteric agonist with canonical LBP binding affinity of 2 nM. |
| PC-62344 |
SR 16832
|
SR 16832 is a dual-site, covalent and allosteric antagonist of PPARγ, inhibits cellular allosteric activation of PPARγ by rosiglitazone. |
| PC-61599 |
T3D-959
|
T3D 959 (DB-959) is a potent, brain penetrant, orally active dual PPARδ/PPARγ agonist with EC50 of 19/297 nM, respectively. |
| PC-61381 |
Lenabasum
|
A synthetic nonpsychoactive cannabinoid acid with potent analgesic and anti-inflammatory activity in vivo, binds directly and selectively to PPARγ. |
| PC-61068 |
BMS-711939
|
A potent and selective human PPARα agonist with EC50 of 4 nM, >1,000-fold selectivity over human PPARγ (EC50=4.5 uM) and PPARδ (EC50 >100 uM) in PPAR-GAL4 transactivation assays. |
| PC-60333 |
SR-1664
|
A novel potent, non-agonist PPARγ ligand that blocks the Cdk5-mediated phosphorylation in vitro (IC50=80 nM) and in vivo, without the classical agonism. |
| PC-45391 |
Pemafibrate racemate
|
The racemate of Pemafibrate, which is a highly potent, specific PPARα agonist with EC50 of 1 nM.. |
| PC-45697 |
DG-172 dihydrochloride
|
DG-172 is a novel PPARβ/δ-selective ligand showing high binding affinity (IC50= 27 nM) and potent inverse agonistic properties. |
