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Cat. No. Product Name Information
PC-20856

LY3127760

EP4 antagonist

LY3127760 is a potent, selective prostaglandin E4 (EP4) receptor antagonist with binding Ki of 58 nM (hEP4) and cAMP IC50 of 5.6 nM.
PC-49034

KMN-159

EP4 agonist

KMN-159 is a potent, selective small-molecule full agonist of the prostaglandin E2 type 4 (EP4) receptor with Ki of 0.24 nM (rEP4) and EC50 of 10.6 nM in the BMC ALP assays, with no affinity for EP2 (Ki>10,000 nM).
PC-38844

OC000459

DP2 (CRTh2) inhibitor

OC000459 is a potent, selective, and orally active D prostanoid receptor 2 (DP2, CRTH2) antagonist with Ki of 13/3 nM for human/recombinant DP2, respectively.
PC-72851

TG8-260

EP2 antagonist

TG8-260 is a second-generation, potent, selective EP2 antagonist with Schild KB of 13.2 nM.
PC-38004

HL-43

EP4 antagonist

HL-43 (EP4 antagonist HL-43) is a selective prostaglandin E receptor 4 (EP4) antagonist, promotes chondrocyte differentiation/cartilage regeneration and anabolism with low toxicity.
PC-36058

BGC20-1531

BGC20-1531 (PGN-1531, AP 1531) is a potent, selective prostanoid EP receptor EP antagonist, exhibits high affinity at recombinant human EP4 receptors expressed in cell lines (pKB=7.6) and native EP4 receptors in human cerebral and meningeal artery (pKB=7.6-7.8).
PC-36057

BAY-1316957

BAY-1316957 (BAY 1316957) is a highly potent, selective, orally available human prostaglandin E2 receptor subtype 4 (hEP4-R) antagonist with IC50 of 15.3 nM.
PC-35836

PGN-9856

EP2 receptor agonist

PGN-9856 (PGN9856) is a novel potent, selective prostaglandin EP2 receptor agonist with pKi of > 8.3, shows high selectivity over EP1 , EP3 , EP4 , DP, FP, IP and TP receptors.
PC-35542

ASP7657

EP4 antagonist

ASP7657 (ASP-7657) is a potent, selective, orally active prostaglandin EP4 receptor antagonist with Ki values of 6.02 nM and 2.21 nM for rat and human EP4 receptors, resepctively.
PC-35221

CR6086 sodium

EP4 antagonist

CR6086 sodium (CR-6086) is a potent, selective prostaglandin E2 receptor 4 (EP4) antagonist with Ki of 16.6 nM (hEP4 receptor), inhibits PGE2-stimulated cAMP production with IC50 of 22 nM.
PC-63545

E7046

E7046 (Palupiprant, ER-886046) is a potent, selective, orally bioavailable EP4 receptor antagonist with IC50 of 13.5 nM, Ki of 23.14 nM.
PC-62041

U-46619

TP agonist

U-46619 is a potent and stable thromboxane A2 (TP) receptor agonist with EC50 of 35 nM.

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