| Cat. No. |
Product Name |
Information |
| PC-49574 |
TG11-77
PEG2 receptor inhibitor
|
TG11-77 is a potent, selective, brain-permeable and orally available antagonist of the prostaglandin E2 (PGE2) receptor subtype EP2 with KB value of 9.7 nM. |
| PC-38519 |
ONO-8130
EP1 antagonist
|
ONO-8130 is a selective, orally bioavailable antagonist of prostaglandin E2 (PGE2) receptor EP1 with Ki value of 1.9 nM, >1,000-fold selectivity for EP1 over other EP receptors. |
| PC-36059 |
MF-766
|
MF-766 (MF766) is a highly potent and selective EP(4) antagonist with binding Ki of 0.23 nM, displays no significant affinity (>7000-fold selectivity) against other PG receptors (IC50>1500 nM). |
| PC-35509 |
MK-8318
|
MK-8318 (MK8318) is a potent, selective, orally available CRTh2 receptor antagonist with Ki of 5 nM, shows nM potency in functional assay (cAMP IC50=8 nM, β-Arrestin IC50=3.5 nM. |
| PC-35403 |
Omidenepag Isopropyl
|
Omidenepag Isopropyl (DE-117, OMDI) is the prodrug of Omidenepag, which is a potent, selective agonist human EP2 receptor. |
| PC-35402 |
Omidenepag
|
Omidenepag is a potent, selective agonist human EP2 receptor with binding IC50/EC50 of 10/1.7 nM, >500-fold selectivity over EP1, EP3 and EP4 receptors. |
| PC-35353 |
RO1138452
|
RO1138452 is a potent, selective antagonist of prostacyclin receptor (IP receptor), inhibits carbaprostacylin-stimulated c-AMP accumulation in human SH-SY5Y neuroblastoma cells with pKb of 8.8. |
| PC-35079 |
OBE022
|
OBE022 is a potent, highly selective, orally active antagonist of the contractile PGF2α prostaglandin receptor with Kb of 5.9 nM, shows no activity for other human PG receptors subtypes. |
| PC-63431 |
ADC-3680
|
ADC-3680 (PTR-36, ADC-3680B) is a potent, selective prostaglandin D2 receptor (DP2, CRTH2) antagonist for the treatment of asthma.. |
| PC-63430 |
MK-1029
|
ADC-3680 is a potent, selective prostaglandin D2 receptor (DP2, CRTH2) antagonist for the treatment of asthma.. |
| PC-63365 |
ONO-DI 004
|
ONO-DI 004 is a potent, selective EP1 agonist.. |
| PC-63350 |
GSK726701A
|
GSK726701A is a novel potent, selective EP4 receptor partial agonist with pEC50 of 7.4 in cAMP accumulation assay, >100-fold against a set of other prostaglandin receptors (EP1-3, DP1, FP, IP and TP). |
