| Cat. No. |
Product Name |
Information |
| PC-20108 |
Y-33075
ROCK inhibitor
|
Y-33075 (Y33075) is a potent, selective ROCK inhibitor with IC50 of 3.6 nM, more potent than Y-27632. |
| PC-49062 |
ROCK inhibitor 23
ROCK inhibitor
|
ROCK inhibitor 23 is a potent, selective, and brain-penetrant Rho kinase (ROCK) inhibitor with IC50 of 6 nM. |
| PC-38732 |
RKI-1447
ROCK inhibitor
|
RKI-1447 is a potent small molecule inhibitor of ROCK1 and ROCK2 with IC50 of 14.5 nM and 6.2 nM, respectively, suppresses phosphorylation of the ROCK substrates MLC-2 and MYPT-1 in human cancer cells. |
| PC-38731 |
RKI 1447 dihydrochloride
ROCK inhibitor
|
RKI-1447 is a potent small molecule inhibitor of ROCK1 and ROCK2 with IC50 of 14.5 nM and 6.2 nM, respectively, suppresses phosphorylation of the ROCK substrates MLC-2 and MYPT-1 in human cancer cells. |
| PC-73191 |
KD025
ROCK2 inhibitor
|
KD025 (Belumosudil, SLx-2119) is a potent, selective ROCK2 inhibitor with IC50 of 105 nM. |
| PC-35737 |
SB772077B
ROCK inhibitor
|
SB772077B (SB-772077B, SB77, SB-772077-B) is a potent, selective Rho kinase (ROCK) inhibitor with IC50 of 5.6 nM and 6.0 nM for ROCK1 and ROCK2, respectively. |
| PC-35150 |
DJ4
ROCK/MRCK inhibitor
|
DJ4 (ROCK inhibitor DJ4) is a potent, selective, ATP-competitive inhibitor of ROCK1/2 and MRCKα/β with IC50 of 5/50 nM and 10/100 nM, respectively. |
| PC-43479 |
SR-3677
ROCK2 inhibitor
|
SR-3677 is a potent and selective ROCK-II inhibitor with biochemical IC50 of 3 nM, inhibits myosin light chain bisphosphorylation (ppMLC) with IC50 of 3.5 nM in cell-based assays. |
| PC-63524 |
BDP5290
|
BDP5290 (BDP00005290) is a potent myotonic dystrophy kinase-related CDC42-binding kinase (MRCK) inhibitor with Ki of 10/4 nM for MRCKα/β, respectively. |
| PC-63523 |
BDP9066
MRCK inhibitor
|
BDP9066 (BDP-9066) is a highly potent and selective Myotonic dystrophy-related Cdc42-binding kinase MRCK inhibitor with IC50 of 43 nM, >100-fold selectivity over related ROCK1 or ROCK2. |
| PC-63522 |
BDP8900
MRCK inhibitor
|
BDP8900 (BDP-8900) is a highly potent and selective Myotonic dystrophy-related Cdc42-binding kinase MRCK inhibitor with IC50 of 43 nM (MRCKβ), >100-fold selectivity over related ROCK1 or ROCK2. |
| PC-62716 |
Netarsudil dihydrochloride
|
Netarsudil (AR-13324) is a potent, selective ROCK inhibitor with Ki of 4.2 nM for ROCK2. |
