| Cat. No. |
Product Name |
Information |
| PC-61252 |
FPND
ROCK1 inhibitor
|
FPND (FPMINT) is a novel specific ROCK1 kinase inhibitor with IC50 of 11.2 uM, without inhibitory activity against ROCK2. |
| PC-60681 |
PF-4950834
ROCK inhibitor
|
PF-4950834 is a potent, selective, ATP-competitive and orally acitve Rho kinase (ROCK) inhibitor with IC50 of 33.1 and 8.5 nM for ROCK1 and ROCK2, respectively. |
| PC-42222 |
Y-39983
ROCK inhibitor
|
Y-39983 (Y-33075 hydrochloride) is a potent and selective p160 ROCK inhibitor with Ki of 140 nM. |
| PC-22185 |
SB772077B dihydrochloride
ROCK inhibitor
|
SB772077B dihydrochloride (SB-772077B, SB77) is a potent, selective Rho kinase (ROCK) inhibitor with IC50 of 5.6 nM and 6.0 nM for ROCK1 and ROCK2, respectively. |
| PC-21755 |
C3TD879
Citron kinase inhibitor
|
C3TD879 is a potent, selective first-in-class Citron kinase (CITK) chemical inhibitor with biochemical IC50 of 12 nM. |
| PC-21300 |
ITRI-E-(S)4046
ROCK/MYLK4 inhibitor
|
ITRI-E-(S)4046 (E(S)4046) is a potent, highly specific, dual synergistic inhibitor of myosin light chain kinase 4 (MYLK4) and Rho-related protein kinase (ROCK) with IC50 of 3.2 nM and 25.6 nM for ROCK1 and MYLK4, respectively. |
| PC-20109 |
Y-33075 dihydrochloride
ROCK inhibitor
|
Y-33075 dihydrochloride (Y33075) is a potent, selective ROCK inhibitor with IC50 of 3.6 nM, more potent than Y-27632. |
| PC-20085 |
(S)-BA-1049
ROCK2 inhibitor
|
(S)-BA-1049 is a potent, orally-available ROCK2-selective inhibitor with IC50 of 0.24 uM, 16-fold selectivity over ROCK-1. |
| PC-20084 |
(R)-BA-1049
ROCK2 inhibitor
|
(R)-BA-1049 is a potent, orally-available ROCK2-selective inhibitor with IC50 of 0.24 uM, 16-fold selectivity over ROCK-1. |
| PC-38353 |
Cotosudil
ROCK inhibitor
|
Cotosudil is a small molecule Rho-associated (ROCK) kinase inhibitor. |
| PC-43437 |
Thiazovivin
|
Thiazovivin is a small molecule inhibitor of ROCK, dramatically improves (200-fold) the efficiency of iPSC generation from human fibroblasts. |
| PC-62715 |
Verosudil
|
Verosudil (AR-12286) is a potent ROCK inhibitor (Ki=0.2 nM) that effectively lowers intraocular pressure (IOP) in animal models and human subjects . |
