| Cat. No. |
Product Name |
Information |
| PC-62205 |
Diazepinomicin
|
Diazepinomicin (TLN 4601, ECO-4601) is a brain penetrant inhibitor of Ras-RAF-MAPK pathway post Ras prenylation and prior to MEK activation, binds the central and/or peripheral benzodiazepine receptors (PBR, TSPO). |
| PC-60732 |
ONO-2952
TSPO inhibitor
|
ONO-2952 is a novel potent, selective, orally active translocator protein 18 kDa (TSPO/PBR) antagonist with Ki of 0.33-9.3 nM for both rat and human TSPO, respectively. |
| PC-70052 |
DAA-1097
|
A potent, selective agonist of PBR/TSPO that inhibits [3H]PK 11195 binding to crude mitochondrial preparations of rat whole brain with IC50 of 0.92 nM.. |
| PC-45756 |
DAA-1106
|
A potent, selective agonist of peripheral benzodiazepine receptor (PBR/TSPO) that inhibits [3H]PK 11195 binding to crude mitochondrial preparations of rat whole brain with IC50 of 0.92 nM. |
| PC-72081 |
FGIN-1-27
TSPO agonist
|
FGIN-1-27 is an anxiolytic compound that acts as a selective agonist at the peripheral benzodiazepine receptor (TSPO). |
| PC-62197 |
DPA-714
|
DPA-714 is a potent, selective ligand for the translocator protein (TSPO) with Ki of 7.0 nM. |
| PC-60733 |
CB34
|
A potent, selective translocator protein 18 kDa (TSPO/PBR) agonist with IC50 of 2.59 and 1.03 nM in competing with [3H]-PK11195 for binding to membrane preparations from rat cerebral cortex and ovary, respectively. |
| PC-60195 |
Ro5-4864
|
A potent, selective ligand for the mitochondrial translocator protein 18kDa (TSPO/PBR). |
| PC-60185 |
PK-11195
|
An isoquinoline carboxamide that binds selectively to PBR (TSPO) with Ki of 3.1 nM in cerebellum, 4.1 nM in spinal cord. |
