| Cat. No. |
Product Name |
Information |
| PC-49382 |
PA-915
PAC1 receptor antagonist
|
PA-915 (PA915) is a small-molecule, non-peptide antagonist of the PACAP type I (PAC1) receptor, inhibits PACAP (1 nM)-induced phosphorylation of CREB in PAC1/CHO cells with IC50 of <10 pM. |
| PC-72883 |
PA-8
PAC1 antagonist
|
PA-8 (PAC1 antagonist PA-8) is a potent, pecific small molecule antagonist of PACAP type I (PAC1) receptor. |
| PC-20945 |
BAY 2686013
PAC1 receptor antagonist
|
BAY 2686013 is a selective, allosteric antagonist of human pituitary adenylate cyclase activating polypeptide receptor (hPAC1-R) with IC50 of 0.92 and 0.4 uM in cAMP HTRF and Ca2+ release assays, respectively. |
| PC-20663 |
VPAC2 antagonist 1
VIPR2 antagonist
|
VPAC2 antagonist 1 is a small molecule human vsoactive intestinal peptide receptor-2 (hVIPR2, hVPAC2 receptor) antagonist, inhibits VPAC2-mediated cAMP accumulation with IC50 of 3.8 uM and the ligand-activated beta-arrestin2 binding with IC50 of 2.3 uM. |
| PC-20662 |
VIPR1 antagonist 41
VIPR1 antagonist
|
VIPR1 antagonist 41 is a potent, selective vsoactive intestinal peptide receptor-1 (VIPR1) antagonist with cAMP IC50 of 0.29 uM. |
| PC-20661 |
BAY 55-9837
VIPR2 agonist
|
BAY 55-9837 is a potent, highly selective peptide agonist of vasoactive intestinal peptide receptor 2 (VIPR2, VPAC2 receptor) with Kd of 0.65 nM, >100-fold selectivity over VPAC1. |
| PC-20660 |
Ro 25-1553
VIPR2 agonist
|
Ro 25-1553 is a potent, selective VIPR2 agonist and a cyclic peptide analog of vasoactive intestinal peptide (VIP), displaces the radioligand 125I-VIP from rat forebrain membranes with IC50 of 4.98 nM. |
| PC-20659 |
KS-133
VIPR2 antagonist
|
KS-133 (KS133) is a potent, selective bicyclic peptide antagonist of vasoactive intestinal peptide receptor 2 (VIPR2) with IC50 of 24.8 nM in Ca influx assays. |
