| Cat. No. |
Product Name |
Information |
| PC-38395 |
Gemnelatinib
c-Met inhibitor
|
Gemnelatinib (GST-HG161) is a potent and highly selective, orally bioavailable c-Met inhibitor, displays significant antitumor activity in preclinical models, has the potential to be effective in HCC with active c-Met signaling. |
| PC-38394 |
Fosgonimeton
HGF/MET modulator
|
Fosgonimeton (ATH-1017, ATH-1001 prodrug) is a highly specific, small-molecule positive modulator of the HGF/MET neurotrophic system, is a prodrug that rapidly converts into the active metabolite ATH-1001 in plasma. |
| PC-63568 |
BMS-817378
|
BMS-817378 is a prodrug of the dual Met/VEGFR-2 inhibitor BMS-794833.. |
| PC-42833 |
PF-04217903 methanesulfonate
|
PF-04217903 is a potent, selective, ATP-competitive c-Met kinase inhibitor with Ki of 4.8 nM, inhibits HGF-stimulated tyrosine phosphorylation of wild type c-Met with IC50 of 7.3 nM in cell-based assays. |
| PC-60929 |
MET inhibitor Compound 1
|
A novel potent, selective orally bioavailable MET tyrosine kinase inhibitor with IC50 of <1 nM and 12 nM for unphosphorylated and phosphorylaed MET, respectively. |
