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Cat. No. Product Name Information
PC-20515

Sparsentan

Dual AT-II and ETA antagonist

Sparsentan (RE-021, DARA-a) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Ki values of 0.8 and 9.3 nM, respectively.
PC-72732

DCP1-3

AT1R allosteric modulator

DCP1-3 is a novel allosteric ligand of the angiotensin receptor AT1R, displays NAM potency on AngIV with IC50 of 0.29 uM.
PC-43383

EMA401

AT2R inhibitor

EMA401 (Olodanrigan) is a potent, highly selective angiotensin II type 2 receptor (AT2R) antagonist, inhibits capsaicin responses in cultured neurons of human and rat DRG with IC50 of 10 nM.
PC-44124

Azilsartan

AT1 inhibitor

Azilsartan (TAK-536) is a specific and potent angiotensin II type 1 receptor (AT1) antagonist with IC50 of 2.6 nM, used in the treatment of adults with essential hypertension.
PC-22028

BIO101

MasR agonist

BIO101 (20-hydroxyecdysone, Crustecdysone) is a small molecule agonist of Mas receptor (MasR), has anti-inflammatory, anti-fibrotic and cardioprotective properties, shows potential treatment for respiratory failure in COVID-19.
PC-21225

AVE-0991

Angiotensin-(1-7) agonist

AVE 0991 is a potent, selective nonpeptide and orally active angiotensin-(1-7) receptor Mas agonist, displaces the binding of 125I-Ang-(1-7) in Mas-transfected monkey kidney cells (COS) cells with IC50 of 47.5 nM.
PC-21224

A779

Angiotensin-(1-7) inhibitor

A779 is a potent, selective antagonist of angiotensin-(1-7) receptor Mas, blocks the antidiuretic effect of Ang-(1-7) in vivo.
PC-49657

Forasartan

AT1 receptor inhibitor

Forasartan (SC-52458) is a potent, specific, competitive and reversible angiotensin II receptor (AT1 receptor) antagonist with binding Ki value of 2.9 nM.
PC-73402

Azilsartan mopivabil

AT2R antagonist

Azilsartan mopivabil is a potent, selective angiotensin II receptor (AT2R) antagonist, with potential for hypertension, chronic heart failure and diabetic nephropathy.
PC-73401

Azilsartan mepixetil

AT2R antagonist

Azilsartan mepixetil is a potent, selective angiotensin II receptor antagonist, with potential for hypertension, chronic heart failure and diabetic nephropathy.
PC-35877

TD-0212

TD-0212 (TD0212) is a potent, orally efficacious, dual AT1 antagonist/Neprilysin (NEP) inhibitor with pKi of 8.9 (AT1) and pIC50 of 9.2 (NEP).
PC-43020

CGP-42112

CGP-42112 (CGP42112A) is a highly potent, selective Angiotensin-II subtype 2 receptor(AT2 receptor) agonist with Ki of 0.24 nM.

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