| Cat. No. |
Product Name |
Information |
| PC-20170 |
MRI-1891
CB1R antagonist
|
MRI-1891 (INV-202) is potent, selective, β-Arrestin-2-biased peripheral cannabinoid-1 receptor (CB1R) antagonist with Ki of 0.3 nM (hCB1R), >2000-fold CB1R/CB2R selectivity. |
| PC-20082 |
AM251
CB1 antagonist
|
AM251 (AM 251) is a potent, selective CB1 receptor antagonist (inverse agonist) with IC50 of 8 nM, Ki of 7.49 nM, displays 306-fold selectivity over CB2 receptors. |
| PC-49218 |
S-777469
CB2 agonist
|
S-777469 (S777469) is a potent, selective, orally available cannabinoid receptor 2 (CB2) receptor agonist with Ki value of 32 nM (hCB2), >100-fold selectivity over CB1. |
| PC-47097 |
LY2828360
CB2 agonist
|
LY2828360 is a potent CB2 receptor agonist with similar affinity for human and rat CB2 receptors with Ki of 40.3 nM and 36.7 nM, respectively, shows EC50 of 20.1 nM in [35S]-GTPγS assays. |
| PC-38638 |
JM-00266
CB1 inverse agonist
|
JM-00266 is a novel non-brain penetrant cannabinoid receptor 1 (CB1R) inverse agonist with cAMP EC50 of 248.6 nM in HEK293T/17 cells transfected with murine CB1R. |
| PC-73454 |
Vicasinabin
CB2 agonist
|
Vicasinabin (RG7774, RG-7774) is a potent, selective agonist of cannabinoid receptor 2 (CB2) with cAMP EC50 of 1 nM (hCB2), >800-fold selectivity over CB1 receptor. |
| PC-73251 |
ZCZ011
CB1 receptor PAM
|
ZCZ011 is a positive allosteric modulator of CB1 receptor, increases specific binding of CB1 receptor orthosteric agonist [3H]CP55,940 to mouse brain membranes with pEC50 of 6.9. |
| PC-72731 |
PSNCBAM-1
CB1 antagonist
|
PSNCBAM-1 is an allosteric antagonist of CB1 receptor with IC50 of 22.5 nM in Ca2+ assays, inhibits [3H]CP55,940 binding with EC50 of 167 nM. |
| PC-72730 |
RTICBM-189
CB1 NAM
|
RTICBM-189 is a potent, selective, brain-penetrant CB1 negative allosteric modulator (NAM) with pIC50 of 7.54 in Ca2+ assay, 5.29 in GTPγS assay. |
| PC-72729 |
RTICBM-229
CB1 NAM
|
RTICBM-229 is a potent, selective, brain-penetrant CB1 negative allosteric modulator (NAM) with IC50 of 169 nM in Ca2+ assay, 40 nM in GTPγS assay. |
| PC-72728 |
RTICBM-74
CB1 NAM
|
RTICBM-74 is a potent, selective, brain-penetrant CB1 negative allosteric modulator (NAM) with IC50 of 23 nM in Ca2+ assays. |
| PC-35625 |
XL-001
CB2 inverse agonist
|
XL-001 (XL001) is a novel specific CB2 inverse agonist with Ki of 0.5 nM. |
