| Cat. No. |
Product Name |
Information |
| PC-20892 |
NJNU-0069-003
MHC-II inducer
|
NJNU-0069-003 is a specific small-molecule inducer of major histocompatibility complex class II (MHC-II), directly binds to the MAT domain of FASN with Kd of 7.98 uM. |
| PC-72780 |
TVB3664
FASN inhibitor
|
TVB3664 is a potent, selective and highly bioavailable fatty acid synthase (FASN) inhibitor with IC50 of 18 nM and 12 nM for human and mouse cell palmitate synthesis, respectively |
| PC-72346 |
TVB-2640
FASN inhibitor
|
TVB-2640 (Denifanstat, TVB2640) is a first-in-class, potent, selective, oral fatty acid synthase (FASN) inhibitor with IC50 of 52 nM, inhibits lipogenesis with therapeutic potential against NAFLD, nonalcoholic steatohepatitis, and KRAS MUT solid tumors. |
| PC-35893 |
IPI-9119
FASN inhibitor
|
IPI-9119 (IPI9119) is a potent, selective, and irreversible inhibitor of fatty acid synthase (FASN) with IC50 of 0.3 nM in biochemical assays. |
| PC-35031 |
BI-99179
FASN inhibitor
|
BI-99179 is a potent and selective inhibitor of type I fatty acid synthase (FAS) with IC50 of 79 nM. |
| PC-43135 |
FAS-IN-1
FASN inhibitor
|
FAS-IN-1 (FASN-IN-1) is a potent inhibitor of fatty acid synthase (FAS, FASN) wtih IC50 of 10 nM. |
| PC-43006 |
trans-C75
FASN inhibitor
|
trans-C75 is an enantiomer of FASN inhibitor C75, which is a synthetic, slow-binding inhibitor of mammalian FAS, binds to and inhibits mammalian FAS and inhibits fatty acid synthesis in human cancer cells (SKBR3 cells ID50=3.2 ug/mL). |
| PC-43005 |
FASN inhibitor C75
FASN inhibitor
|
FASN inhibitor C75 is a synthetic, slow-binding inhibitor of mammalian fatty acid synthesis (FASN, FAS), binds to and inhibits mammalian FAS and inhibits fatty acid synthesis in human cancer cells (SKBR3 cells ID50=5.0 ug/mL). |
| PC-42976 |
GSK2194069
|
GSK2194069 is a potent and specific inhibitor of the β-ketoacyl reductase (KR) activity of human fatty acid synthase (hFAS) with IC50 of 7.7 nM (CoA release). |
| PC-62734 |
TVB-3166
FASN inhibitor
|
TVB-3166 is an orally-available, reversible, potent, and selective fatty acid synthase (FASN) inhibitor with biochemical IC50 of 42 nM. |
| PC-21673 |
FASstatin
FASN inhibitor
|
FASstatin (FASNi-8) is an orally bioavailable small-molecule inhibitor of fatty acid synthase (FASN), directly binds FASN with SPR KD of 16 uM, potentiates TRIM56-mediated FASN ubiquitination. |
| PC-21269 |
CMS121
FASN inhibitor
|
CMS121 is a small molecule fatty acid synthase (FASN) inhibitor, reduces lipid peroxidation and neuroinflammation both in vitro and in vivo. |
