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Request The Product List ofIndoleamine 2,3-Dioxygenase (IDO) Indoleamine 2,3-Dioxygenase (IDO)

Cat. No. Product Name Information
PC-72378

BMS-986242

IDO1 inhibitor

BMS-986242 (BMS986242) is a potent, selective IDO1 inhibitor with IC50 of 2 nM in cellular IDO1 inhibition assays and IC50 of 25 nM in human whole blood (HWB) IDO1 inhibition assays.
PC-38081

PCC0208009

IDO inhibitor

PCC0208009 is a novel indoleamine 2,3-dioxygenase (IDO) inhibitor with IC50 of 4.52 nM at the cellular level.
PC-60068

BMS-986205

BMS-986205 (Linrodostat, F-001287, ONO-7701) is a novel potent, selective and orally available IDO1 inhibitor with IC50 of 1.1 nM in cell-based assays.
PC-45552

Navoximod

Navoximod (GDC-0919, NLG-919) is a potent, selective inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1) with biochemical IC50 of 28 nM, and of Ki of 5.8 nM.
PC-45061

Indoximod

Indoximod (NLG-8189, 1-Methyl-D-tryptophan, D-1MT) is a potent Indoleamine 2,3-dioxygenase (IDO) inhibitor with IC50 of 7 uM.
PC-42320

PF-06840003

PF-06840003 is a novel potent, selective, orally active, and CNS penetrant IDO-1 inhibitor with IC50 of 0.41 uM for hIDO-1.
PC-20021

Apoxidole-1

Apo-IDO1 inhibitor

Apoxidole-1 is a potent, selective type IV inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), Apoxidole-1 reduce cellular kynurenine (Kyn) levels with IC50 of 46.7 in HeLa cells, but does not inhibit IDO1 expression.
PC-49663

NLG-802

IDO inhibitor

NLG-802 (NLG802) is a next-generation indoleamine-2,3-dioxygenase (IDO) pathway inhibitor and a prodrug of indoximod, shows increased oral bioavailability and maximum exposure.
PC-49659

LY3410738

mutant IDH1 inhibitor

LY3410738 (LY 3410738) is a potent, selective, and covalent inhibitor of mutant IDH1 (IDH1-R132), LY3410738 is more effective than Ivosidenib (Cat#PC-45550) and potentiates antileukemic activity of AML.
PC-73168

LY-3381916

IDO1 inhibitor

LY-3381916 is a potent, selective and brain-penetrant Indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with IC50 of 7 nM.
PC-35777

VIS351

VIS351 (VIS-351) is a potent activator of the immunoreceptor tyrosine-based inhibitory motif (ITIM)-mediated function of the IDO1 enzyme with Kd of 1.9 uM.
PC-35526

Roxyl-WL

Roxyl-WL is a highly potent and selective inhibitor of IDO1 with IC50 of 1 nM.

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