Cat. No. |
Product Name |
Information |
PC-22041 |
NLRP3 inhibitor NIC-12
NLRP3 inhibitor
|
NIC-12 is a highly potent broad-spectrum NLRP3 inhibitor, inhibits NLRP3 inflammasome activation (IL-1β release) in mouse macrophages with IC50 of 11 nM. |
PC-21813 |
NDT-19795
NLRP3 inhibitor
|
NDT-19795 is the carboxylic acid metabolite of selective NLRP3 inhibitor NT-0796, suppresses release of IL-1β in LPS-activated human PBMCs with IC50 of 47 nM. |
PC-21079 |
JT002
NLRP3 inhibitor
|
JT002 is a potent and selective inhibitor of NLRP3 inflammasome with IC50 of 6 nM (IL-1β production from hPBMCs), inhibits NLRP3 mediated cytokine production and pyroptosis. |
PC-20912 |
JT001
NLRP3 inhibitor
|
JT001 (JT-001) is a potent, highly specific NLRP3 inhibitor, inhibits NLRP3 inflammasome assembly. |