| Cat. No. |
Product Name |
Information |
| PC-62110 |
LY 2456302
KOR antagonist
|
LY 2456302 (CERC-501, JSPA 0658, Aticaprant) is a potent, selective, short-acting antagonist of κ-opioid receptor (KOR) with Ki of 0.81 nM. |
| PC-61682 |
Oliceridine hydrochloride
|
Oliceridine hydrochloride (Olinvo, TRV130) is a potent, selective, and G protein biased μ opioid receptor (MOR) agonist with pEC50 of 8.1. |
| PC-61681 |
Oliceridine
|
Oliceridine (Olinvo, TRV130) is a potent, selective, and G protein biased μ opioid receptor (MOR) agonist with pEC50 of 8.1. |
| PC-61588 |
MK-1925
ORL1 agonist
|
MK-1925 is a selective, orally active, brain-penetrant opioid receptor-like 1 (ORL1. |
| PC-61545 |
J-113397
ORL1 agonist
|
J-113397 is a potent, selective nociceptin/orphanin FQ receptor (NOP receptor/ORL1) antagonist with IC50 of 2.3 nM. |
| PC-61544 |
Ro 64-6198
NOP agonist
|
Ro 64-6198 is a nonpeptidic, selective, brain-penetrant agonist of nociceptin/orphanin FQ receptor (NOP receptor/ORL1) with pKi of 9.41. |
| PC-61543 |
Ro 64-6198 hydrochloride
ORL1 agonist
|
Ro 64-6198 hydrochloride is a nonpeptidic, selective, brain-penetrant agonist of nociceptin/orphanin FQ receptor (NOP receptor/ORL1) with pKi of 9.41. |
| PC-61542 |
MT-7716
ORL1 agonist
|
A highly potent, brain-penetrating ORL1 receptor (NOP receptor) agonist with Ki of 0.76 and 0.50 nM for rat and human ORL1 receptors, respectively. |
| PC-61541 |
W-212393
ORL1 agonist
|
W-212393 (MT-7716 free base) is a highly potent, brain penetrant ORL1 receptor (NOP receptor) agonist with Ki of 0.76 and 0.50 nM for rat and human ORL1 receptors, respectively. |
| PC-61540 |
SR-16835
NOP receptor agonist
|
SR-16835 is a potent full agonist of ORL1 receptor (NOP receptor) with binding Ki of 11.4 nM, with low-affinity mu-opioid partial agonist activity (Ki=79.9 nM). |
| PC-61539 |
SR-16507
ORL1 agonist
|
SR-16507 is a potent full agonist of ORL1 receptor (NOP receptor) and partial agonist of mu-opioid receptor with Ki of 5.22 nM and 1.07 nM, respectively. |
| PC-61538 |
SR-16430
ORL1 inhibitor
|
SR-16430 is a selective ORL1 receptor (NOP receptor) antagonist that has 10-fold selectivity over μ-opioid receptor. |
