| Cat. No. |
Product Name |
Information |
| PC-20962 |
MRS4833
P2Y14 inhibitor
|
MRS4833 is a potent, selective antagonist of Gi protein-coupled P2Y14 receptor (P2Y14R, GPR105) with IC50 of 5.9 nM, Ki of 3.44 nM (human P2Y14R). |
| PC-20961 |
MRS4654
P2Y14 inhibitor
|
MRS4654 is a potent, selective antagonist of Gi protein-coupled P2Y14 receptor (P2Y14R, GPR105) with IC50 of 15 nM and 18.6 nM for human and rat P2Y14R, respectively. |
| PC-20960 |
MRS4738
P2Y14 inhibitor
|
MRS4738 is a potent, selective antagonist of Gi protein-coupled P2Y14 receptor (P2Y14R, GPR105) with IC50 of 3.11 nM. |
| PC-20959 |
MRS4608
P2Y14 inhibitor
|
MRS4608 is a potent, selective antagonist of Gi protein-coupled P2Y14 receptor (P2Y14R, GPR105) with IC50 of 6.32 nM. |
| PC-20648 |
AZD1283
P2Y12 antagonist
|
AZD1283 (AZD-1283) is a potent, selective P2Y12 receptor antagonist with binding IC50 of 11 nM, and IC50 of 3.2 uM in washed platelet assay (WPA). |
| PC-49620 |
MRS4853
P2Y6 inhibitor
|
MRS4853 is a selective P2Y6 receptor (P2Y6R) antagonist with IC50 of 0.46 uM (hP2Y6R), displays weak affinity for mP2Y6R (IC50=6.15 uM). |
| PC-35578 |
ACT-281959
|
ACT-281959 (ACT281959) is the prodrug of ACT-246475, which is a potent, selective, reversible P2Y12 receptor antagonist with binding IC50 of 1.0 nM. |
| PC-35049 |
MRS4478
|
MRS4478 is a potent, highly specific amtagonist of P2Y14 receptor with IC50 of 269 nM, does not display extensive off-target interactions with biogenic amine receptors.. |
| PC-35048 |
MRS4458
|
MRS4458 is a potent, highly specific amtagonist of P2Y14 receptor with IC50 of 169 nM, does not display extensive off-target interactions with biogenic amine receptors.. |
| PC-63561 |
BMS-884775
|
BMS-884775 is a potent, selective P2Y1 antagonist with IC50 of 0.12 nM. |
| PC-43381 |
MRS 2578
|
MRS2578 is a potent, selective P2Y6 receptor antagonist with IC50 of 37 nM (human) and 101 nM (rat). |
| PC-61744 |
MRS 2179 tetrasodium
|
MRS 2179 is a potent, selective, competitive P2Y1 receptor antagonist with Kb of 100 nM. |
