| Cat. No. |
Product Name |
Information |
| PC-61628 |
STAT5b inhibitor 7
STAT5b inhibitor
|
STAT5b inhibitor 7 (Capstafin prodrug) is the pivaloyloxymethyl ester prodrug of Capstafin, which is a potent, selective STAT5b inhibitor with Ki of 0.34 uM. |
| PC-61476 |
SC99
STAT3 inhibitor
|
SC99 is a novel selective STAT3 inhibitor that inhibits JAK2-STAT3 activation but has no effects on other transcription factors such as NF-κB, and kinases such as AKT, ERK, and c-Src. |
| PC-61312 |
IQDMA
STAT3/5 inhibitor
|
IQDMA is a cell-permeable, small molecule inhibitor of the transcription factor STAT5, and dual STAT3/5 degrader (IC50=0.54-1.63 μM). |
| PC-61311 |
STAT5-IN-1
|
STAT5-IN-1 is a selective, small molecule inhibitor of the transcription factor STAT5 with IC50 of 47±17 uM in FP assays. |
| PC-61260 |
BP-5-087
STAT3 inhibitor
|
BP-5-087 is a potent, selective STAT3 SH2 domain inhibitor (EC50=5.6 uM) that reduces STAT3 phosphorylation and nuclear transactivation. |
| PC-61235 |
Indirubin E804
STAT3 inhibitor, Src inhibitor
|
Indirubin E804 is an indirubin derivative that potently blocks constitutive STAT3 signaling in human breast and prostate cancer cells, directly inhibits Src kinase activity (IC50=0.43 uM) in vitro. |
| PC-70249 |
STA-21
STAT3 inhibitor
|
STA-21 (NSC 628869, Ochromycinone) is a small-molecule inhibitor of STAT3, inhibits Stat3 DNA binding activity, Stat3 dimerization, and Stat3-dependent luciferase activity (20-30 uM). |
| PC-70361 |
Piperlongumine
STAT3 inhibitor
|
Piperlongumine (Piplartine) is a naturally occurring small molecule recently identified to be toxic selectively to cancer cells in vitro and in vivo, binds and targets STAT3 Cys712 residue. |
| PC-70277 |
OPB-31121
|
OPB-31121 (OPB31121) is a novel STAT3 inhibitor (IC50=18.7 nM, Kd=10 nM) that strongly inhibits STAT3 and STAT5 phosphorylation without upstream kinase inhibition. |
| PC-61169 |
Pomstafib-2
STAT5b inhibitor
|
Pomstafib-2 is the pivaloyloxymethyl ester prodrug of Stafib-2, which is a potent, selective STAT5b inhibitor with Ki of 9 nM. |
| PC-61168 |
Pomstafib-1
STAT5b inhibitor
|
Pomstafib-1 is the cell-permeable, pivaloyloxymethylester of Stafib-1, which is a potent, selective small molecule inhibitor of transcription factor STAT5b with Ki of 44 nM, >50-fold selectivity over STAT5a. |
| PC-61167 |
Stafib-2
|
Stafib-2 (Stafib 2) is a potent, selective small molecule inhibitor of transcription factor STAT5b with Ki of 9 nM, >20-fold selectivity over STAT5a.. |
