| Cat. No. |
Product Name |
Information |
| PC-42174 |
BP-1-102
STAT3 inhibitor
|
BP-1-102 is an orally bioavailable, small-molecule inhibitor of STAT3 with Kd of 504 nM. |
| PC-42160 |
HO-3867
STAT3 inhibitor
|
HO-3867 is a synthetic curcuminoid that selectively inhibits STAT3 phosphorylation, transcription, and DNA binding without affecting the expression of other active STATs. |
| PC-42175 |
SH5-07
STAT3 inhibitor
|
SH5-07 (SH-5-07, SH 5-07) is a potent, selective small-molecule STAT3 inhibitor with IC50 of 3.9 uM. |
| PC-45109 |
SH-4-54
STAT3 inhibitor
|
SH-4-54 is a potent, BBB permeable, nonphosphorylated STAT3 inhibitor that strongly binds to STAT3 protein with Kd of 300 nM. |
| PC-43790 |
Napabucasin
STAT3 inhibitor
|
Napabucasin (BBI608) is a potent small-molecule inhibitor of STAT3 that has a broad spectrum of activity against stemness-high cancer cells (IC50=0.5-1.5 uM). |
| PC-42210 |
AS1517499
STAT6 inhibitor
|
AS1517499 is a novel potent STAT6 inhibitor with IC50 of 21 nM in STAT6-dependent promoter reporter assay. |
| PC-25692 |
STAT6 ligand-1
STAT6 ligand
|
STAT6 ligand-1 is a specific ligand of STAT6 used for synthesizing STAT6 PROTAC degraders. |
| PC-25691 |
STAT6-IN-10
STAT6 inhibitor
|
STAT6-IN-10 is a potent, selective STAT6 inhibitor with IC50 of 1.2 uM in STAT6 reporter assay using STAT6-HEK293 cells. |
| PC-25690 |
STAT6-IN-9
STAT6 inhibitor
|
STAT6-IN-9 is a potent, selective STAT6 inhibitor with EC50 of 4 nM, efficiently blocks the STAT6 activation process mediated by the IL-13-IL-13 receptor/IL-4 receptor pathway, potently inhibits CCL17 secretion with IC50 of 4.6 nM. |
| PC-25689 |
STAT6-IN-7
STAT6 inhibitor
|
STAT6-IN-7 is a potent, selective STAT6 inhibitor with IC50 of 0.28 uM in STAT6 reporter assay using STAT6-HEK293 cells. |
| PC-25688 |
STAT6-IN-8
STAT6 inhibitor
|
STAT6-IN-8 is a potent, selective STAT6 inhibitor with IC50 of 0.25 uM in STAT6 reporter assay using STAT6-HEK293 cells. |
| PC-25579 |
Bt354
STAT3 inhibitor
|
Bt354 is a specific, small-molecule inhibitor of the STAT3 signalling pathway, prevents STAT3 from entering the nucleus and phosphorylates it at Y705, exhibiting potent anticancer properties. |
