| Cat. No. |
Product Name |
Information |
| PC-61470 |
Rac1-IN-6
Rac1 inhibitor
|
Rac1-IN-6 is a selective small molecule Rac1 inhibitor that blocks Rac1-PAK1 complex formation with IC50 of 88±48 nM. |
| PC-61469 |
Rac1-IN-1
Rac1 inhibitor
|
Rac1-IN-1 is a selective small molecule Rac1 inhibitor that blocks Rac1-PAK1 complex formation with IC50 of 95±21 nM. |
| PC-61468 |
MLS000532223
Rho GTPases inhibitor
|
MLS000532223 is a high affinity, selective inhibitor of Rho family GTPases with EC50 of 16-120 uM. |
| PC-61174 |
SecinH3
small GEFs inhibitor
|
SecinH3 is a selective inhibitor of small GEFs of the cytohesin family, blocks human, mouse and Drosophila cytohesins with IC50 of 2.4 to 5.6 uM. |
| PC-60905 |
MBQ-167
Rac/Cdc42 inhibitor
|
MBQ-167 (MBQ 167, MBQ167) is a potent, dual Rac/Cdc42 inhibitor with IC50 of 103/78 nM, respectively, in metastatic breast cancer cells. |
| PC-60847 |
Nexinhib 20
Rab27a inhibitor
|
Nexinhib 20 is a novel small molecule neutrophil exocytosis inhibitor (IC50=0.33 uM) that specifically inhibits Rab27a-JFC1 binding (IC50=2.6 uM) but does not interfere with the interaction of other Rab GTPases and effectors. |
| PC-60611 |
NAV 2729
ARF6 inhibitor
|
NAV 2729 (NAV2729) is a novel, direct and selective small molecule inhibitor of small GTPase ARF6 with IC50 of 1.5 uM in nucleotide exchange assays. |
| PC-44661 |
NSC 23766 trihydrochloride
Rac inhibitor
|
NSC 23766 trihydrochloride is a specific small molecule inhibitor of Rac GTPase. |
| PC-44660 |
NSC 23766
Rac inhibitor
|
NSC 23766 (NSC23766) is a specific small molecule inhibitor of Rac GTPase.
|
| PC-43811 |
ZCL278
Cdc42 inhibitor
|
ZCL278 is a potent, cell-permeable Cdc42-specific small-molecule inhibitor (Kd=6.4 uM). |
| PC-20881 |
PREX-in1
P-Rex inhibitor
|
PREX-in1 is a specific small-molecule inhibitor of P-Rex1 and P-Rex2 Rac-GEF activity with IC50 of 4.5 uM (P-Rex1 DHPH Rac-GEF activity) in liposome-based GEF assay, inhibits P-Rex1 and P-Rex2 through their catalytic DH domain. |
| PC-20183 |
GYS32661
RAC1 inhibitor
|
GYS32661 (GYS 32661) is a potent Rac inhibitor capable of inhibiting both Rac1 and Rac1b, inhibited activated Rac1 with IC50 of 1.18 uM in in vitro pull-down assays. |
