| Cat. No. |
Product Name |
Information |
| PC-60847 |
Nexinhib20
Rab27a-JFC1 inhibitor
|
Nexinhib20 is a specific small molecule neutrophil exocytosis inhibitor (IC50=0.33 uM) that specifically inhibits Rab27a-JFC1 binding (IC50=2.6 uM) but does not interfere with the interaction of other Rab GTPases and effectors. |
| PC-60611 |
NAV-2729
ARF6 inhibitor
|
NAV-2729 (NAV2729) is a novel, direct and selective small molecule inhibitor of small GTPase ARF6 with IC50 of 1.5 uM in nucleotide exchange assays. |
| PC-44661 |
NSC 23766 trihydrochloride
Rac inhibitor
|
NSC 23766 trihydrochloride is a specific small molecule inhibitor of Rac GTPase. |
| PC-44660 |
NSC 23766
Rac inhibitor
|
NSC 23766 (NSC23766) is a specific small molecule inhibitor of Rac GTPase.
|
| PC-43811 |
ZCL278
Cdc42 inhibitor
|
ZCL278 is a potent, cell-permeable Cdc42-specific small-molecule inhibitor (Kd=6.4 uM). |
| PC-27402 |
Acmiribine
Rac1 inhibitor
|
Acmiribine (8-Hydroxy-2-deoxyguanosine, 8-OHdG) is a small molecule Rac1 inhibitor, suppresses NO production and COX-2 activity via Rac1/STATs signaling in LPS-induced brain microglia. |
| PC-26767 |
(R)-Ketorolac
Cdc42/Rac1 inhibitor
|
(R)-Ketorolac (R-ketorolac) is a small molecule allosteric Cdc42 and Rac1 GTPases inhibitor, significantly inhibits cell adhesion, migration and invasion in ovarian cancer cells. |
| PC-26551 |
Ran inhibitor M36
RAN GTPase inhibitor
|
Ran inhibitor M36 (Ran-IN-1) is a specific small molecule inhibitor of Ran GTPase, inhibits Ran-GTP activation, has IC50 of 10.02 uM in clonogenic assays for TOV112D cell line. |
| PC-25187 |
Rac1 Inhibitor W56
RAC1 inhibitor
|
Rac1 Inhibitor W56 is a peptide inhibitor of Rac1 containing residues 45-60 of Rac1, inhibits Rac1 interaction with guanine nucleotide exchange factors TrioN, GEF-H1, and Tiam. |