Trk Receptor (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-60903	LOXO-195 R racemate Trk inhibitor	The R racemate of LOXO-195, a potent, selective, next-generation Trk tyrosine kinase inhibitor with IC50 of 0.6 nM and <2.5 nM for WT TrkA and WT TrKC, respectively..
PC-60901	Selitrectinib Trk inhibitor	LOXO-195 (Selitrectinib, LOXO195) is a potent, selective, next-generation Trk tyrosine kinase inhibitor with IC50 of 0.6 nM and <2.5 nM for WT TrkA and WT TrKC, respectively.
PC-70173	Lestaurtinib JAK2/FLT3 inhibitor	Lestaurtinib (KT-5555, CEP-701) is a potent, orally active JAK2, FLT3 and TrkA inhibitor with IC50 of 0.9 nM, 3 nM and < 25 nM, respectively.
PC-70172	CEP-751 Trk inhibitor	CEP-751 (KT-6587) is potent inhibitor of TrkA with IC50 of 2.9 nM, also inhibits TrkB, TrkC.
PC-70171	K252a TRK inhibitor	K252a (SF2370) is a potent, non-selective tyrosine protein kinase inhibitor for Trk family, CaMK and other phosphorylase kinases.
PC-45453	GW441756 TrkA inhibitor	GW441756 is a potent, specific TrkA inhibitor with IC50 value of 2 nM.
PC-23114	ACD856 pan-Trk PAM	ACD856 is a potent, pan-Trk positive allosteric modulator (PAM) with EC50 of 382 nM, 295 nM and 33 nM for TrkA, TrkB and TrkC respectively.
PC-60902	LOXO-195 RS-isomer	The RS-isomer of LOXO-195, a potent, selective, next-generation Trk tyrosine kinase inhibitor with IC50 of 0.6 nM and <2.5 nM for WT TrkA and WT TrKC, respectively..

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