| Cat. No. |
Product Name |
Information |
| PC-60029 |
Acrizanib
|
Acrizanib (LHA510, LHA-510) is a novel potent, selective VEGFR-2 (KDR) inhibitor with IC50 of 17.4 nM in cell-based assays. |
| PC-42701 |
EG00229
VEGF-A/NRP1 inhibitor
|
EG00229 is the first small molecule ligand for the VEGF-A receptor neuropilin 1 (NRP1), selectively inhibits radiolabeled 125I-VEGF-A binding to PAE/NRP1 with IC50 of 8 uM. |
| PC-42637 |
Telatinib
VEGFR inhibitor
|
Telatinib (Bay 57-9352) is an orally active, small molecule inhibitor of VEGFR-2 (IC50=6 nM), VEGFR-3 (IC50=4 nM), PDEGFRα (IC50=15 nM) and c-Kit (IC50=1 nM) in biochemical assays. |
| PC-42130 |
NVP-BAW2881
VEGFR inhibitor
|
NVP-BAW2881 is a potent, selective VEGFR inhibitor with IC50 of 37 nM for hVEGFR2 (KDR). |
| PC-42471 |
Motesanib
VEGFR inhibitor
|
Motesanib (AMG-706) is a potent, orally bioavailable, multikinase inhibitor inhibitor of VEGFR1/2/3, PDGFR and c-Kit with IC50 of 2-6 nM, 84 nM and 8 nM, respectively. |
| PC-42834 |
Vatalanib
VEGFR inhibitor
|
Vatalanib (PTK787) is a potent, orally available class III receptor tyrosine kinases inhibitor with IC50 of <1 uM for VEGFR, Flt-1, KDR and PDGFRβ. |
| PC-45898 |
Nintedanib
VEGFR inhibitor
|
Nintedanib (BIBF-1120) is a potent triple angiokinase (VEGFR/PDGFR/FGFR) inhibitor with IC50 of 5/38/18/104/5 nM for VEGFR-2/FGFR-1/PDGFRα/VEGFR-1/VEGFR-3, respectively. |
| PC-45859 |
Linifanib
|
Linifanib (ABT-869) is a potent multi-RTKs inhibitor of members of VEGFR and PDGFR families with IC50 of 4/3/3/14/4/66/190/170 nM for KDR/FLT1/CSF1R/KIT/FLT3/PDGFRβ/FLT4/Tie2, respectively. |
| PC-42530 |
Regorafenib
VEGFR inhibitor
|
Regorafenib (BAY 73-4506) is a potent multikinase inhibitor that potently inhibits endothelial cell kinases in biochemical and cellular kinase phosphorylation assays with nanomolar range (IC50=3-200 nM). |
| PC-42498 |
Vandetanib hydrochloride
VEGFR2 inhibitor
|
Vandetanib hydrochloride is a potent and selective VEGFR2 (KDR) inhibitor with IC50 of 40 nM. |
| PC-42496 |
Vandetanib
VEGFR2 inhibitor
|
Vandetanib (ZD6474) is a potent and selective VEGFR2 (KDR) inhibitor with IC50 of 40 nM. |
| PC-45746 |
Fruquintinib
VEGFR inhibitor
|
Fruquintinib (HMPL-013) is a potent and highly selective small molecule inhibitor of VEGFR1/2/3 with IC50 of 33/3/5/0.5 nM, respectively. |
