| Cat. No. |
Product Name |
Information |
| PC-70290 |
R-116010
|
A potent CYP26A1 inhibitor with IC50 of 10 nM, potently inhibits all-trans-retinoic acid metabolism in intact T47D cells with IC50 of 8.7 nM. |
| PC-60700 |
BI 689648
|
A novel potent, selective, orally active aldosterone synthase inhibitor with IC50 of 2 nM, displays 150-fold selectivity over related cortisol synthase. |
| PC-60699 |
Fadrozole hydrochloride
|
A potent and selective, orally bioavailable aromatase inhibitor with IC50 of 1.7 nM, 180 times more potent than aminoglutethimide. |
| PC-60698 |
Fadrozole
|
A potent and selective, orally bioavailable aromatase inhibitor with IC50 of 1.7 nM, 180 times more potent than aminoglutethimide. |
| PC-42290 |
CDD3506
|
A small molecule inducer of hepatic cytochrome P450IIIA (CYP3A), produces significant increases in HDL cholesterol.. |
| PC-42289 |
CDD3505
|
A small molecule inducer of hepatic cytochrome P450IIIA (CYP3A), produces significant increases in HDL cholesterol.. |
| PC-45788 |
Methoxsalen
|
A potent tricyclic furocoumarin suicide that used to treat psoriasis, eczema, vitiligo and some cutaneous lymphomas in conjunction with exposing the skin to sunlight. |
| PC-45614 |
TMS
|
A potent and selective inhibitor of the EROD activity of P450 1B1 with IC50 of 6 nM. |
| PC-45937 |
Abiraterone
|
A potent and irreversible CYP17A1 inhibitor with IC50 of 4 nM for 17α-hydroxylase. |
| PC-45958 |
Abiraterone acetate
|
A potent and irreversible CYP17 inhibitor. |
| PC-45936 |
TOK-001
|
A potent 17α-hydroxylase/17,20-lyase (CYP17) inhibitor with IC50 of 300 nM. |
| PC-45969 |
Bergaptol
|
A natural furanocoumarin that is found to be a potent inhibitor of debenzylation activity of CYP3A4 enzyme with IC50 of 24.92 uM. |
