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Request The Product List ofDeubiquitinase (DUB) Deubiquitinase (DUB)

Cat. No. Product Name Information
PC-38692

FT709

USP9X inhibitor

FT709 is a potent, highly selective USP9X inhibitor with IC50 of 82 nM in biochemical assays, reduces CEP55 expression in BxPC3 pancreatic cancer cells with IC50 of 131 nM.
PC-73355

Subquinocin

CYLD inhibitor

Subquinocin is a small molecule inhibitor of DUB activity of CYLD with IC50 of 30 uM, enhances NF-κB activation by inhibiting CYLD.
PC-72836

NJH-2-075

OTUB1 recruiter DUBTAC

NJH-2-075 is an alkyne-functionalized probe of EN523, retains binding to OTUB1 in vitro.
PC-72835

EN523

OTUB1 recruiter DUBTAC

EN523 (EN-523) is a small molecule covalent ligand that targets a non-catalytic allosteric cysteine C23 in the K48-ubiquitin-specific deubiquitinase OTUB1, OTUB1 recruiter component of DUBTAC NJH-2-057.
PC-72699

MT16-001

UCHL1 inhibitor

MT16-001 is a selective, covalent inhibitor of deubiquitinating enzyme UCHL1 with IC50 of 580 nM, no inhibitory effect against UCHL3 (IC50>30 uM).
PC-72535

HBX-90659

USP8 inhibitor

HBX-90659 (compound 22 e) is a potent, selective USP8 inhibitor with IC50 of 0.28 uM, with no effect on USP7 (IC50 of >100 uM).
PC-72253

FT385

USP30 inhibitor

FT385 (FT3967385) is a potent, selective USP30 inhibitor with biochemical IC50 of 1.5 nM.
PC-72252

USP30 inhibitor Compound 39

USP30 inhibitor

USP30 inhibitor Compound 39 (CMPD-39) is a highly selective inhibitor of USP30 with IC50 of 20 nM in an in vitro assay of enzyme activity, >100-fold selectivity over other DUBs.
PC-38192

USP7-866

USP7 inhibitor

USP7-866 is a novel potent selective inhibitor of USP7 with IC50 of 0.18 nM.
PC-38191

USP7-797

USP7 inhibitor

USP7-797 is a novel potent selective inhibitor of USP7 with IC50 of 0.44 nM.
PC-38173

FT206

USP28 inhibitor

FT206 (FT-206, FT3951206, CRT0511973) is a potent, selectivel inhibitor of USP28 with a remarkable USP28/25 selectivity.
PC-38156

XL-9872-106C

JOSD1/USP30/UCHL1 inhibitor

XL-9872-106C (XL-106C) is a potent, selective inhibitor of the deubiquitinase (DUB) JOSD1/USP30/UCHL1 with IC50 of 134/390/166 nM, respectively.

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