Cat. No. |
Product Name |
Information |
PC-42479 |
R-7128
|
The prodrug of PSI-6130, a potent, specific inhibitor of HCV RNA synthesis by inhibiting the NS5B RNA polymerase.. |
PC-42589 |
R-1479
|
A potent, specific inhibitor of HCV NS5B polymerase and HCV replication (IC50=1.28 uM, replicon assay). |
PC-42477 |
Boceprevir
|
A potent, selective, orally bioavailable HCV NS3 protease with Ki of 14 nM, EC90 of 350 nM in cell replicon assays. |
PC-42481 |
Vaniprevir
|
A potent, selective, orally available inhibitor of HCV NS3/4A protease with Ki of 0.05 and 0.9 nM for GT1b and 2a protease, respectively. |
PC-42476 |
Telaprevir
|
A potent, selective, covalent, orally bioavailable inhibitor of HCV NS3/4A protease with Ki of 7 nM. |
PC-42515 |
Narlaprevir
|
A potent, second generation HCV NS3 serine protease inhibitor with Ki of 6 nM. |
PC-42480 |
Simeprevir
|
A potent, orally available inhibitor of HCV NS3/4A protease with Ki of 0.36 nM, replicon EC50 of 7.8 nM. |
PC-42478 |
Danoprevir
|
A potent, highly selective, orally available, peptidomimetic HCV NS3/4A protease inhibitor with IC50 of 0.2-0.4 nM (GT1a, 1b, 4, 5 and 6), 1.6 nM (GT2b). |
PC-42722 |
RO-9187
|
A potent HCV NS5B RNA polymerase inhibitor. |
PC-42603 |
Daclatasvir dihydrochloride
|
A potent HCV NS5A inhibitor with EC50 of <50 pM against genotype 1 replicons. |
PC-45961 |
VX-222
|
A potent and selective, nonnucleoside inhibitor of HCV NS5B polymerase inhibitor with Kd of 17 nM. |
PC-42023 |
Peretinoin
|
A novel orally available, synthetic retinoid with potential antineoplastic and chemopreventive activities. |