| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-38083 |
Izilendustat
|
1303512-02-8 |
Izilendustat is a potent inhibitor of HIF prolyl hydroxylase (PHD) which stabilizes hypoxia inducible factor- 1 alpha (HIF- lα), as well as hypoxia inducible factor-2 (HIF-2).. |
| PC-62044 |
KHS-101
|
1262770-73-9 |
KHS-101 (KHS101) is a small molecule that selectively induces a neuronal differentiation phenotype, induces neuronal differentiation in cultured hippocampal neural progenitor cells (NPCs) by interacting with TACC3 (EC50=1 uM). |
| PC-61213 |
JNJ-42905343
|
1238689-36-5 |
JNJ-42905343 is a potent, selective, orally active prolyl hydroxylase (PHD) inhibitor with pKi of 8.07, 7.48 and 7.27 for PHD1, PHD2 and PHD3 respectively. |
| PC-60509 |
Desidustat
|
1616690-16-4 |
Desidustat (ZYAN1) is a novel HIF prolyl hydroxylase (PHD) inhibitor under clinical development for the treatment of anemia. |
| PC-60370 |
IDF-11774
|
1429054-28-3 |
IDF-11774 (IDF 11774, IDF11774) is a potent, orally bioavailable HIF-1 inhibitor that reduces the HRE-luciferase activity of HIF-1α (IC50=3.65 uM) and blocks HIF-1α accumulation under hypoxia in HCT116 human colon cancer cells. |
| PC-60317 |
PT-2399
|
1672662-14-4 |
PT-2399 (PT 2399, PT2399) is a selective, potent HIF-2α antagonist that binds directly to the HIF2α PAS B domain. |
| PC-45660 |
THS-044
|
62054-67-5 |
THS-044 is a low micromolar HIF2α PAS-B binding compound (Kd=2 uM). |
