| Cat. No. |
Product Name |
Information |
| PC-73187 |
S1P5-IN-15
S1P5 antagonist
|
S1P5-IN-15 is a potent, selective, orally active and brain-penetrant S1P5 antagonist with IC50 of 0.1 nM, no effect on S1P1-4. |
| PC-72368 |
SAR247799
S1P1 agonist
|
SAR247799 is a potent, selective G protein-biased S1P1 agonist with EC50 of 39 and 19 nM in β-arrestin and internalization assays, respectivey. |
| PC-43245 |
S1P1 Agonist 8
|
S1P1 Agonist 8 is a potent, selective, orally bioavailable S1P1 receptor agonist with EC50 of 35 nM (S1P1 internalization), >100-fold selectivity over against receptor subtypes S1P2-5. |
| PC-45411 |
LPA2-IN-1
|
A potent, selective LPA2 (EDG4) antagonist with IC50 of 17 nM. |
| PC-42341 |
S1p receptor agonist 1
|
A potent S1P receptor agonist extracted from patent WO 2015039587 A1, compound example 2.. |
