| Cat. No. |
Product Name |
Information |
| PC-36037 |
Fuzuloparib
|
Fluzoparib (Fuzuloparib, SHR-3162) is a novel, potent and orally available inhibitor of PARP with IC50 of 1.46 nM (PARP1). |
| PC-36012 |
PARP10 inhibitor 22
PARP10 inhibitor
|
PARP10 inhibitor 22 is a selective, cell-active inhibitor of PARP10 with IC50 of 1.8 uM, exhibits >10-fold selectivity over a large subset of other PARP family members. |
| PC-36007 |
MSC2504877
TNKS1/2 inhibitor
|
MSC2504877 (MSC-2504877) a novel small molecule selective tankyrase inhibitor with IC50 of 0.7/0.8 nM against TNKS1/2, shows 771-fold selectivity for TNKS1 over PARP1 (IC50=0.54 uM). |
| PC-35720 |
PARP11 inhibitor ITK7
|
PARP11 inhibitor ITK7 (ITK7) is a potent and selective PARP11 inhibitor with IC50 of 14 nM, displays >200-fold selectivity over other PARPs. |
| PC-35703 |
RK-287107
TNKS1/2 inhibitor
|
RK-287107 (RK287107) is a novel potent, tankyrase-specific inhibitor with IC50 of 14.3 and 10.6 nM for tankyrase-1 (TNKS1) and tankyrase-2 (TNKS2) respectively, shows no activity against PARP-1. |
| PC-35646 |
Gemcabene calcium
PARP activator
|
Gemcabene (PD-72953, PD72953) is a first-in-class lipid-lowering agent and activator of PARP. |
| PC-35643 |
Gemcabene
PARP activator
|
Gemcabene (PD-72953, PD72953) is a first-in-class lipid-lowering agent and activator of PARP. |
| PC-35508 |
ME0328
|
ME0328 (ME-0328) is a potent, selective inhibitor of ADP-ribosyltransferase ARTD3/PARP3 with IC50 of 0.89 uM. |
| PC-35506 |
ZYTP1
PARP1/2 inhibitor
|
ZYTP1 is a novel, oral PARP inhibitor that inhibits PARP1, PARP2, Tankyrase-1 and Tankyrase-2 with IC50 of 5.4, 0.7, 133.3 and 289.8 nM, respectively. |
| PC-35437 |
Amelparib
PARP1 inhibitor
|
Amelparib (JPI-289, JPI289) is a novel potent, water soluble PARP-1 inhibitor with IC50 of 18.5 nM, inhibits cellular PAR formation with IC50 of 10.7 nM. |
| PC-35378 |
OUL35
PARP10 inhibitor
|
OUL35 (NSC39047) is a potent and selective inhibitor of mono-ADP-ribosyltransferase PARP10/ARTD10 with IC50 of 330 nM, displays remarkable selectivity towards ARTD10 over other enzymes in the human protein family. |
| PC-63335 |
UPF1854
TNKS1 inhibitor
|
UPF1854 is a potent tankyrase inhibitor with IC50 of 12 nM and 200 nM for TNKS1 and TNKS-2 respectively, displays no cross-reactivity versus other PARP proteins. |
