| Cat. No. |
Product Name |
Information |
| PC-20289 |
WJM228
P.f Cyt bc1 inhibitor
|
WJM228 (WJM-228) is a potent selective inhibitor of P. falciparum cytochrome bc1, targets the Qo site of cytochrome b (cyt b), shows potent parasite activity against P. falciparum 3D7 with EC50 of 19 nM. |
| PC-20266 |
Genz-667348
Pf DHODH inhibitor
|
Genz-667348 (Genz667348) is a potent, selective P. falciparum DHODH inhibitor with IC50 of 22, 14 and 42 nM for PfDHODH, PbDHODH and PvDHODH, respectively. |
| PC-20265 |
DSM502
Pf DHODH inhibitor
|
DSM502 (DSM 502) is a potent, selective inhibitor of P. falciparum and P. vivax DHODH with IC50 of 20 and 14 nM, respectively. |
| PC-20262 |
DSM267
DHODH inhibitor
|
DSM267 (DSM 267) is a potent, highly selective, long-duration and orally bioavailable malaria DHODH inhibitor. |
| PC-20261 |
DSM705
DHODH inhibitor
|
DSM705 (DSM 705) is a potent, highly selective, long-duration and orally bioavailable malaria DHODH inhibitor with IC50 of 95 nM (PfDHODH). |
| PC-49850 |
DSM186
AbDHODH inhibitor
|
DSM186 (DSM 186) is a high potent A. baumannii DHODH (AbDHODH) inhibitor with IC50 of 28 nM, has MIC <1 ug/mL against geographically diverse A. baumannii strains, including meropenem-resistant isolates. |
| PC-49849 |
DSM161
AbDHODH inhibitor
|
DSM161 (DSM 161) is a high potent A. baumannii DHODH (AbDHODH) inhibitor, has MIC <1 ug/mL against geographically diverse A. baumannii strains, including meropenem-resistant isolates. |
| PC-49833 |
WEHI-600
Pf PMX inhibitor
|
WEHI-600 is a potent, small molecule inhibitor of the aspartic proteases Plasmepsin X (PMX) with IC50 of 3 nM, possess potent anti-parasitic activity (P. falciparum parasite, IC50=7 nM). |
| PC-49832 |
WEHI-601
Pf PMX inhibitor
|
WEHI-601 is a potent, small molecule inhibitor of the aspartic proteases Plasmepsin X (PMX) with IC50 of 5 nM, possess potent anti-parasitic activity (P. falciparum parasite, IC50=9 nM). |
| PC-49831 |
CWHM-117
Pf PM-II inhibitor
|
CWHM-117 is potent nanomolar inhibitor of the Plasmodium aspartic proteases PM-II and PM-IV with IC50 of 4 and 15 nM respectively, exhibits IC50 of 463 nM in the Pf 3D7 infected RBC assays. |
| PC-49830 |
TCMDC-136879
|
TCMDC-136879 is a cyclic acyl guanidine compound with antimalarial activity. |
| PC-49829 |
WM382
Pf PMX inhibitor
|
WM382 (WM-382) is a potent, specific dual inhibitor of the aspartic proteases Plasmepsin IX and X (PMIX and PMX) with IC50 of 0.06 nM (PMX), blocks multiple stages of the Plasmodium life cycle. |
