| Cat. No. |
Product Name |
Information |
| PC-21094 |
WEHI-518
PfPI4KIIIB inhibitor
|
WEHI-518 is a small molecule inhibitor of the parasite's phosphatidylinositol kinase PfPI4KIIIB, shows EC50 of 22 nM against blood-stage P. falciparum parasites. |
| PC-21087 |
MMV396797
PfPI4KIIIB inhibitor
|
MMV396797 is a small molecule inhibitor of the parasite's phosphatidylinositol kinase PfPI4KIIIB, block parasite protein secretion and export. |
| PC-20947 |
Cyanotriazole CT3
Parasite Topo II inhibitor
|
Cyanotriazole CT3 is a potent, selective, irreversible inhibitor of trypanosomal topoisomerase II, shows potent trypanocidal activity both in vitro and in vivo. |
| PC-20941 |
JC-229
TbRPA1 inhibitor
|
JC-229 is a small-molecule inhibitor that selectively blocks DNA-binding by Trypanosoma brucei replication protein A1 (TbRPA1), exhibits growth inhibition of T. brucei with EC50 of 6.6 uM. |
| PC-20587 |
ML276
PfG6PDH inhibitor
|
ML276 (ML 276) is a potent, selective inhibitor of Plasmodium falciparum glucose-6-phosphate dehydrogenase (PfG6PDH) with IC50 of 889 nM, with no activity against human G6PD. |
| PC-20586 |
ML304
PfG6PDH inhibitor
|
ML304 (ML 304) is a potent, selective inhibitor of Plasmodium falciparum glucose-6-phosphate dehydrogenase (PfG6PDH) with IC50 of 190 nM, with no activity against human G6PD (IC50=80 uM). |
| PC-20446 |
Nemacol-1
VAChT inhibitor
|
Nemacol-1 is a small molecule inhibitor of C. elegans vesicular acetylcholine transporter (VAChT), demonstrates nematode-selective activity (C. elegans, EC50=7.1 uM). |
| PC-20297 |
P4Q-391
P.f Cyt bc1 inhibitor
|
P4Q-391 is an antimalarial agent with selective inhibition of the parasite's coenzyme Q cycle, inhibits mitochondrial cytochrome bc1 complex (Cyt bc1). |
| PC-20296 |
ELQ-300
P.f Cyt bc1 inhibitor
|
ELQ-300 (ELQ300) is a potent, selective inhibitor of P. falciparummitochondrial cytochrome bc1 complex with IC50 of 0.56 nM. |
| PC-20295 |
ELQ-331
P.f Cyt bc1 inhibitor
|
ELQ-331 (ELQ331) is an alkoxycarbonate prodrug of antimalarial compound ELQ-300 (P. falciparum cytochrome bc1 complex inhibitor), shows P. falciparum IC50 of 6 nM. |
| PC-20294 |
GSK932121
P.f Cyt bc1 inhibitor
|
GSK932121 is a potent, selective inhibitor of P. falciparum cytochrome bc1 with IC50 of 7 nM, binds to Qi site of cytochrome bc1 and shows potent antimalarial activity in vitro and in vivo. |
| PC-20293 |
GW844520
P.f Cyt bc1 inhibitor
|
GW844520 is a potent, selective inhibitor of P. falciparum cytochrome bc1 with IC50 of 2 nM, binds to Qi site of cytochrome bc1 and shows potent antimalarial activity. |
