| Cat. No. |
Product Name |
Information |
| PC-45382 |
Rafoxanide
|
Rafoxanide is a salicylanilide anthelmintic agent that also shows to be an allosteric inhibitor of SPAK and OSR1. |
| PC-45368 |
Buparvaquone
Antiprotozoal
|
Buparvaquone is a hydroxynaphthoquinone antiprotozoal drug related to parvaquone and atovaquone. |
| PC-45379 |
Mebendazole
|
Mebendazole is a highly effective, broad-spectrum antihelmintic by selectively inhibiting the synthesis of microtubules in parasitic worms, and by destroying extant cytoplasmic microtubes in their intestinal cells.. |
| PC-24372 |
WJM280
Pf cyt b inhibitor
|
WJM280 is a potent, specific inhibitor of P. falciparum mitochondrial protein cytochrome b (Pf cyt b), inhibits LDH activity of P. falciparum 3D7 parasites with EC50 of 40 nM. |
| PC-24371 |
WJM664
PfATP4 inhibitor
|
WJM664 is a small molecule inhibitor of P. falciparum malaria P-type ATPase 4 (PfATP4), inhibits P. falciparum 3D7 parasite growth with EC50 of 13 nM. |
| PC-23936 |
YAT2150
Protein aggregation inhibitor
|
YAT2150 is a potent antileishmanial compound and inhibitor of protein aggregation, exhibits potent antiplasmodial activity with IC50 of 90 nM. |
| PC-23895 |
MMV019918
Anti-malaria
|
MMV019918 is a specific small molecule inhibitor of trypanocidal cysteine protease, acts directly against the trypomastigote and the intracellular amastigote forms of T. cruzi at 3 μM. |
| PC-23894 |
MMV019017
Anti-malaria
|
MMV019017 is a small molecule anti-malaria compound, maybe inhibit PfATP4, an ATPase transporter located on the plasma membrane of the malaria parasite. |
| PC-23893 |
PRC1590
P.falciparum inhibitor
|
PRC1590 is a tetrahydro-β-carboline compound that potently kills the malaria parasite with EC50 of 145 nM and 142 nM in growth inhibition assays in 3D7WT and Dd2 strains. |
| PC-23720 |
DSM705 hydrochloride
DHODH inhibitor
|
DSM705 hydrochloride (DSM 705) is a potent, highly selective, long-duration and orally bioavailable malaria DHODH inhibitor with IC50 of 95 nM (PfDHODH), and 52 nM (P. vivax DHODH). |
| PC-23718 |
Cruzipain inhibitor SH-1
Cruzipain inhibitor
|
Cruzipain inhibitor SH-1 is a potent, selective and covalent cysteine protease Cruzipain (CZP) of Trypanosoma cruzi with IC50 of 28 nM, without inhibition on human cathepsin L. |
| PC-23717 |
DSM1465
PfDHODH inhibitor
|
DSM1465 is a potent, selective inhibitor of P. falciparum dihydroorotate dehydrogenase (PfDHODH) with IC50 of 15 nM, inhibits P. falciparum 3D7 (Pf3D7) parasites in whole-cell assays with EC50 of 1.4 nM. |
