| Cat. No. |
Product Name |
Information |
| PC-21997 |
mCMY416
PheRS inhibitor
|
mCMY416 is a potent and selective inhibitor of Toxoplasma gondii phenylalanine tRNA synthetase (PheRS), potently inhibits T. gondii growth with EC90 of 0.38 uM. |
| PC-21960 |
NF2839
SmHDAC8 inhibitor
|
NF2839 is a quinolone-based HDAC inhibitor with IC50 of 0.1 uM for S. mansoni HDAC8 (SmHDAC8), inhibits S. mansoni larval stage with LD50 of 10.6 uM. |
| PC-21811 |
AWZ1066S
Wolbachia inhibitor
|
AWZ1066S is a potent, highly specific anti-Wolbachia inhibitor with EC50 of 2.5 nM against Wolbachia in cell-based assays, and IC50 of 121 nM in microfilaria assays. |
| PC-21802 |
MMV019266
Antibabesial inhibitor
|
MMV019266 is a potent antibabesial inhibitor with IC50 of 0.278 uM and 0.909 uM for Babesia spp. (B. bovis and B. divergens), respectively. |
| PC-21591 |
T. cruzi bc1 inhibitor compound 4
T. cruzi bc1 inhibitor
|
T. cruzi bc1 inhibitor compound 4 is a highly selective and efficacious T. cruzi cytochrome b inhibitor with IC50 of 6 nM, exhibits potent activity against intracellular amastigotes with EC50 of 0.08 uM. |
| PC-21577 |
OJT008
Mtb MetAP1 inhibitor
|
OJT008 is a small molecule Mtb. MetAP inhibitor against M. tuberculosis, has MIC50 of 0.063 µg/mL against both active and MDR Mtb. |
| PC-21553 |
TDI-8304
Pf20S inhibitor
|
TDI-8304 is a highly selective, macrocyclic peptide inhibitor of malaria parasite Plasmodium falciparum proteasome (Pf20S) with IC50 of 0.06 uM, shows high potency against P. falciparum strain Pf 3D7 (EC50=0.009 uM). |
| PC-21550 |
DNDI-6174
Cyt bc1 inhibitor
|
DNDI-6174 is a highly potent inhibitor of Leishmania cytochrome bc1 complex activity, shows broad activity against a panel of representative visceral leishmaniasis clinical isolates from various sources (EC50=10-360 nM). |
| PC-21539 |
MMV693183
Antiparasite
|
MMV693183 is a first-in-class acetyl-CoA synthetase (AcAS) inhibitor and potent antimalarial drug candidate (Asexual blood stage IC50=2.1-2.8 nM). |
| PC-21445 |
CZC-54252
Anti-parasite
|
CZC-54252 is a small molecule inhibitor of five P. falciparum kinases PfARK1, PfARK3, PfNEK3, PfPK9, and PfPKB with IC50 of 3.4, 1.8, 1.0, 1.2 and 0.07 uM, respectively. |
| PC-21377 |
Antitrypanosomal agent 10
Antitrypanosomal
|
Antitrypanosomal agent 10 is a potent, orally active antitrypanosomal compound, selectively inhibits the growth of parasites T. b. brucei, T. b. gambiense and T. b. rhodesiense with EC50 of 0.54, 0.13 and 1.14 uM, resepctively. |
| PC-21135 |
IMP-1002
NMT inhibitor
|
IMP-1002 (IMP1002) is a potent P. falciparum N-myristoyltransferase (PfNMT) inhibitor, potently inhibits parasite growth with EC50 of 34 nM (3D7 strain). |
