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Cat. No. Product Name Information
PC-49827

UCB7362

Pf PMX inhibitor

UCB7362 (UCB 7362) is a potent, selective inhibitor of malaria parasite plasmepsin X (PMX) with IC50 of 7 nM for P. falciparum (Pf PMX) and plasmodium vivax (Pv PMX), SPR Kd of 5.5 nM, also inhibits PMIX with IC50 of 142 nM.
PC-49608

Halofuginol

PfcPRS inhibitor

Halofuginol (MAZ1805) is a halofuginone analog targeting the Plasmodium falciparum prolyl-tRNA synthetase (PfcPRS, Ki=71.1 nM), is highly active against both liver and asexual blood stages of the malaria parasite (EC50=5.8 nM, P. falciparum 3D7 parasite strain).
PC-49604

TBAJ-587

Anti-tuberculosis

TBAJ-587 is a potent anti-tuberculosis agent, inhibits M.tb strain H37Rv growth with MIC90 of 0.006 and <0.02 µg/mL in MABA and LORA assay, respectively.
PC-49005

MBX-4055

P. falciparum PSAC inhibitor

MBX-4055 is a potent and specific antimalarial compound with IC50 of 42 nM (P. falciparum growth inhibition), acts directly on plasmodial surface anion channel (PSAC, Target K0.5=21 nM) to quantitatively abolish parasite-induced permeability changes.
PC-49003

MBX-2366

P. falciparum PSAC inhibitor

MBX-2366 (ISG-21) is a potent and specific antimalarial compound with IC50 of 3 nM (P. falciparum growth inhibition), acts directly on plasmodial surface anion channel (PSAC, Target K0.5=2 nM) to quantitatively abolish parasite-induced permeability changes.
PC-47069

NPD-008

TbrPDEB1 inhibitor

NPD-008 is a potent, selective Trypanosoma brucei PDE B1 (TbrPDEB1) inhibitor with Ki of 100 nM, exhibits antitrypanosomal effects with IC50 of 5.5 uM.
PC-73056

TCMDC-135051

PfCLK3 inhibitor

TCMDC-135051 is a potent PfCLK3 inhibitor with IC50 of 40 nM.
PC-72991

AN7973

Parasite inhibitor

AN7973 (AN-7973) is a novel drug candidate for treatment of cryptosporidiosis, potently inhibits multiple C. parvum isolates and the C. hominis TU502 isolate in vitro.
PC-72957

Pyronaridine

Pf β-hematin inhibitor

Pyronaridine is a fast-acting (chloroquine-like) drug that has the demonstrated ability to inhibit P. falciparum β-hematin formation in vitro, suppress the selection of M5717-resistant mutants.
PC-72956

M5717

PfeEF2 inhibitor

M5717 (DDD107498, M 5717, Cabamiquine) is a potent, specific P. falciparum translation elongation factor 2 inhibitor (PfeEF2).
PC-72936

SBI-0797750

PfGluPho inhibitor

SBI-0797750 (SBI 0797750) is a potent, fully selective PfGluPho inhibitor with robust nanomolar activity against recombinant PfGluPho, PvG6PD, and P. falciparum blood-stage parasites.
PC-72583

CTCB-405

TbPFK inhibitor

CTCB-405 (CTCB405) is a small molecule allosteric inhibitor of T. brucei phosphofructokinase (TbPFK) with IC50 of 0.18 uM, ITC Kd of 92 nM, no significant inhibition of human PFKs.

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