| Cat. No. |
Product Name |
Information |
| PC-42653 |
Ketanserin
5-HT2A antagonist
|
Ketanserin (R41468) is a high-affinity, non-selective antagonist of 5-HT2 receptor with Ki of 2-3 nM for 5-HT2A and 28 nM for 5-HT2C. |
| PC-45229 |
Ziprasidone hydrochloride monohydrate
D2/5-HT2A antagonist
|
Ziprasidone hydrochloride monohydrate (CP-88059) is a full antagonist of D2 and 5-HT2A receptors with Ki of 6.8 and 0.6 nM, respectively. |
| PC-43963 |
Ziprasidone
D2/5-HT2A antagonist
|
Ziprasidone (CP 88059) is a full antagonist of D2 and 5-HT2A receptors with Ki of 6.8 and 0.6 nM, respectively. |
| PC-24462 |
NLX-266
5-HT1A agonist
|
NLX-266 is a potent, selective, orally available and metabolically stable ERK1/2-biased 5-HT1A receptor agonist with binding pKi of 10.35, >1000-fold selective over adrenergic α1 and dopaminergic D2 receptors. |
| PC-24453 |
Brexpiprazole
CAS 913611-97-9
|
Brexpiprazole (OPC-34712) is an atypical orally active antipsychotic agent and partial agonist of human 5-HT1A and dopamine D2L receptor with Ki of 0.12 nM and 0.3 nM, respectively. |
| PC-24324 |
MW073
5-HT2bR inhibitor
|
MW073 is a highly selective and orally bioavailable inhibitor of 5-HT2b receptor (5-HT2bR) with binding IC50 of 70 nM. |
| PC-24283 |
AM1476
5-HT2B inhibitor
|
AM1476 is a highly selective 5-HT2B receptor (5-HT2BR) inhibitor with IC50 of 5.8 nM, showed only low activity at the5-HT2AR (IC50 >10 000 nM) and 5-HT2CR. |
| PC-24221 |
PUC-55
5-HT6R antagonist
|
PUC-10 is a selective 5-HT6 receptor antagonist high binding affinity (Ki=37.5 nM), induces autophagy in the neuroblastoma SH-SY5Y cell line by inhibiting the mTOR pathway. |
| PC-24220 |
PUC-10
5-HT6R antagonist
|
PUC-10 is a selective 5-HT6 receptor antagonist high binding affinity (Ki=14.6 nM) and IC50 of 32 nM in calcium mobilisation functional assay, induces mTOR-dependent autophagy. |
| PC-24197 |
AAZ-A-154
5-HT2R ligand
|
Zalsupindole (AAZ-A-154) is a potent, highly selective non-hallucinogenic psychLight competitive ligand/antagonist of 5-HT2A receptor (5-HT2AR), exhibits antidepressant-like effects. |
| PC-24117 |
Bretisilocin
5-HT2A agonist
|
Bretisilocin is a potent, selective 5-HT2A receptor agonist with the EC50 of 5.54 nM. |
| PC-24116 |
Bretisilocin hydrochloride
5-HT2A agonist
|
Bretisilocin hydrochloride is a potent, selective 5-HT2A receptor agonist with the EC50 of 5.54 nM. |
