| Cat. No. |
Product Name |
Information |
| PC-61178 |
SB-357134
|
A potent, selective, orally active and CNS penetrant 5-HT6 receptor antagonist with pKi of 8.5, displays 1300-fold selectivity over other 13 5-HT receptor subtypes. |
| PC-61117 |
WAY 163909
|
A highly potent, subtype-selective agonist of 5-HT2C receptor with Ki of 10.5 nM, >20-fold selectivity over 5-HT2A and 5-HT2B receptor subtypes (IC50=212 and 485 nM, respectively). |
| PC-61106 |
MIN-117
|
A small molecule 5-HT1A and 5-HT2A receptor antagonist and inhibitor of serotonin and dopamine reuptake, also possess affinity for the α1A- and α1B-adrenergic receptors.. |
| PC-61081 |
PF-03246799
|
A potent and selective 5-HT2C receptor agonist with EC50 of 190 nM, with excellent selectivity for 5-HT2C over 5-HT2A. |
| PC-61080 |
PF-04781340
|
A potent, selective, CNS penetrant 5-HT2C receptor agonist with Ki of 3 nM and EC50 of 9 nM, without significant P-gp efflux liability. |
| PC-60817 |
MK-212
|
A potent, selective 5-HT2C receptor agonist with IC50 of 20 nM in HEK293 cells-exppressed 5-HT2C, shows weakly activity for 5-HT2A. |
| PC-60816 |
BW-723C86
|
A potent, selective 5-HT2B receptor agonist with pKi of 7.1, >10-fold selectivity over 5-HT2A, 5-HT2C, and other 5-HT subtypes. |
| PC-60815 |
RS 102221
|
A highly potent, selective 5-HT2C receptor antagonist with pKi of 8.4 and 8.5 for human and rat 5-HT2C, respectively. |
| PC-60813 |
25CN-NBOH
|
A potent, highly selective and brain-penetrant 5-HT2A receptor agonist with Ki of 1.1 nM ([3H]ketanserin). |
| PC-60522 |
NBUMP
|
A potent, highly selective 5-HT1A receptor partial agonist with Ki of 0.1 nM, displays 460- and 260-fold selectivity for 5-HT1A over the α1-adrenergic and D2 receptors, respectively.. |
| PC-70074 |
Frovatriptan
|
A potent, long lasting 5-HT(1B/1D) receptor agonist as a antimigraine agent.. |
| PC-60046 |
Landipirdine
|
A novel 5-HT receptor antagonist for the treatment of Parkinson's disease.. |
