| Cat. No. |
Product Name |
Information |
| PC-45686 |
ABT-639
T-type calcium channel inhibitor
|
ABT-639 is a novel, peripherally acting, selective T-type calcium channel blocker, blocks recombinant human Cav 3.2 in a voltage-dependent fashion (IC50=2 uM). |
| PC-45854 |
NNC 55-0396
T-type calcium channel inhibitor
|
NNC 55-0396 is a potent and selective T-type calcium channel antagonist that blocks recombinant alpha(1)G T-type channels in human embryonic kidney 293 cellswith IC50 of 7 uM. |
| PC-42314 |
MK-8998
T-type calcium channel inhibitor
|
MK-8998 (Suvecaltamide, CX-8998) is a potent and selective antagonist of the T-type calcium channel for the treatment of schizophrenia. |
| PC-42385 |
NS-638
Sodium channel inhibitor
|
NS-638 is a nonpeptide calcium channel blocker that dose dependently inhibits AMPA-stimulated [3H]GABA-release from cultured cortical neurons with IC50 of 4.3 uM. |
| PC-24336 |
KT-362
Calcium antagonist
|
KT-362 is a small molecule intracellular calcium antagonist, inhibits NE-induced contractions and IP accumulation. |
| PC-23959 |
SERCA1 inhibitor CKP2
SERCA1 inhibitor
|
SERCA1 inhibitor CKP2 is a novel specific inhibitor of sarco/endoplasmic reticulum (ER) calcium ATPase 1 (SERCA1), induces severe ER stress-mediated apoptosis in metastatic PTC cells. |
| PC-23958 |
SERCA1 inhibitor CKP1
SERCA1 inhibitor
|
SERCA1 inhibitor CKP1 is a novel specific inhibitor of sarco/endoplasmic reticulum (ER) calcium ATPase 1 (SERCA1), induces severe ER stress-mediated apoptosis in metastatic PTC cells. |
| PC-23714 |
Ziconotide acetate
N-type calcium channel antagonist
|
Ziconotide acetate (SNX-111 acetate) is a potent and selective block of N-type calcium channels antagonist, reduces synaptic transmission. |
| PC-23713 |
ZC88
CaV2.2 inhibitor
|
ZC88 is a selective N-type calcium channel (CaV2.2) blocker, inhibits recombinant human N-type voltage-sensitive calcium channels (α1B/β1b/α2δ) transiently expressed in HEK-293 cells with IC50 of 0.45 uM. |
| PC-23712 |
C2230
CaV2.2 inhibitor
|
C2230 is a potent, specific CaV2.2 (N-type) calcium channel inhibitor/antagonist with IC50 of 1.3 uM (depolarizing Vh of -50 mV), preferably binds to the inactivated CaV2.2 channels. |
| PC-23650 |
ML218
T-type calcium channel inhibitor
|
ML218 (CID 45115620) is a selective, centrally active T-type Ca(2+) channel inhibitor with IC50 of 310 nM and 270 nM for Cav3.2 and Cav3.3 respectively in patch clamp electrophysiology. |
| PC-23295 |
Dicoumarol
VRAC inhibitor
|
Dicoumarol (Dicumarol) is an inhibitor of both NAD(P)H:quinone oxidoreductase 1 (NQO1) and PDK1 with IC50 of 0.37 and 19.42 uM respectively, also is a potent VRAC inhibitor. |
