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Cat. No. Product Name Information
PC-20729

AZD3778

Dual CCR3/H1 antagonist

AZD3778 (AZD-3778) is a dual CCR3 and H1-receptor antagonistwith Ki of 54 nM for guinea-pig H1-receptor, inhibits binding of CR3 radioligand 125I-eotaxin to human CCR3-receptor expressed on CHO-cells with IC50 of 8 nM.
PC-20728

Ki19003

CCR3 antagonist

Ki19003 (Ki 19003) is a potent, specific CCR3 antagonist, inhibits the CCL11-induced migration of CCR3-expressing L1.2 cells with IC50 of 20 nM.
PC-20727

AZ12436092

CCR3 antagonist

AZ12436092 (AZ 12436092) is a potent, selective CCR3 antagonist with binding pKi value of 9.2.
PC-20726

YM-344031

CCR3 antagonist

YM-344031 is a potent, selective, brain-penetrable CCR3 antagonist with binding IC50 of 3.0 nM, inhibits ligand-induced Ca(2+) flux with IC50 of 5.4 nM.
PC-20725

YM-355179

CCR3 antagonist

YM-355179 is a potent selective, and orally available antagonist of CC chemokine receptor 3 (CCR3) with binding IC50 of 7.6 nM (CCL5).
PC-20724

SB-297006

CCR3 antagonist

SB-297006 is a potent, selective non-peptide CC chemokine receptor-3 (CCR3) antagonist, inhibits 125I-eotaxin binding to human eosinophils with IC50 of 60 nM.
PC-20723

SB-328437

CCR3 antagonist

SB-328437 is a potent, selective non-peptide CC chemokine receptor-3 (CCR3) antagonist, inhibits 125I-eotaxin binding to human eosinophils with IC50 of 4.5 nM.
PC-20542

J-113863

CCR1 inhibitor

J-113863 is a potent, selective, non-peptide antagonist of CCR1 with IC50 of 0.9 and 5.8  nM for human and mouse CCR1 receptors, respectively.
PC-20541

UCB35625

CCR1 inhibitor

UCB35625 is a potent, selective inhibitor of CCR1 and CCR3, inhibits MIP-1α-induced chemotaxis in CCR1 transfectants and eotaxin-induced chemotaxis in CCR3 transfectants with IC50 of 9.57 and 93.8 nM respectively.
PC-20531

INCB3284 bismesylate

CCR2 antagonist

INCB3284 bismesylate (INCB 3284, INCB003284) is a potent, selective and orally bioavailable hCCR2 antagonist with IC50 of 3.7 nM in antagonism of MCP-1 binding to hCCR2 and 4.7 nM in antagonism of chemotaxis activity.
PC-20530

INCB3284

CCR2 antagonist

INCB3284 (INCB 3284, INCB003284) is a potent, selective and orally bioavailable hCCR2 antagonist with IC50 of 3.7 nM in antagonism of MCP-1 binding to hCCR2 and 4.7 nM in antagonism of chemotaxis activity.
PC-20525

INCB9471

CCR5 antagonist

INCB9471 (INCB 9471) is a potent, selective, and orally bioavailable CCR5 antagonist with IC50 of 6.5 nM in MIP-1β assays, exhibits potent anti-HIV-1 activity against ADA and BaL strains with IC50 of 0.36 and 0.16 nM respectively.

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