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Cat. No. Product Name Information
PC-45771

TAK-220

CCR5 antagonist

TAK-220 (TAK220) is a potent, specific, orally bioavailable CCR5 antagonist that blocks the binding of MIP-1α to CCR5 with IC50 of 1.4 nM.
PC-42443

SCH-527123

CXCR2 antagonist

SCH-527123 (Navarixin, MK-7123) is a potent, selective, orally bioavailable CXCR2/CXCR1 receptor antagonist with Kd of 0.08 and 41 nM for cynomolgus CXCR2 and CXCR1, respectively.
PC-42417

CCX140

CCX140 (Ilacirnon, CCX140B) is a potent, selective, orally bioavailable CCR2 antagonist with Kd of 2.3 nM for hCCR2.
PC-45057

SB-225002

CXCR2 antagonist

SB-225002 (SB225002) is a potent, selective, non-peptide CXCR2 antagonist with IC50 of 22 nM.
PC-45905

Plerixafor octahydrochloride

Plerixafor octahydrochloride (JM-3100, AMD-3100, SID-791) is a potent, selective CXCR4 inhibitor (IC50=44 nM) that inhibits the replication of various HIV-1 and HIV-2 strains in various cell lines with EC50 of 10ng/ml.
PC-42164

Plerixafor

Plerixafor (JM-3100, AMD-3100, SID-791) is a potent, selective CXCR4 inhibitor (IC50=44 nM) that inhibits the replication of various HIV-1 and HIV-2 strains in various cell lines with EC50 of 10ng/ml.
PC-45838

INCB-3344

CCR2 antagonist

INCB-3344 (INCB3344) is a potent, selective and orally bioavailable CCR2 antagonist with IC50 of 5.1 nM and 9.5 nM for hCCR2 and mCCR2, respectively, in MCP-1 binding assays.
PC-42073

SCH-546738

CXCR3 inhibitor

SCH-546738 (SCH546738) is a potent, selective and non-competitive CXCR3 antagonist with binding Ki of 0.4 nM for human CXCR3.
PC-42055

SCH-563705

CXCR1/CXCR2 inhibitor

SCH-563705 is a potent, orally bioavailable dual CXCR2/CXCR1 receptor antagonist with IC50 of 1.3 nM and 7.3 nM, respectively.
PC-45199

Vicriviroc maleate

CCR5 antagonist

Vicriviroc maleate (SCH417690) is a potent, highly selective, and orally bioavailable CCR5 antagonist with Ki of 2.5 nM.
PC-45833

MK-0812

CCR2 antagonist

MK-0812 is a potent CCR2 specific antagonist that blocks MCP-1 mediated response with an IC50 of 3.2 nM.
PC-45483

RS102895

CCR2 antagonist

RS-102895 (Abaucin, RS102895) is a potent and specific CCR2 antagonist with binding IC50 of 360 nM, also is a narrow-spectrum activity against A. baumannii.

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