Cat. No. |
Product Name |
Information |
PC-35088 |
GSK812397
CXCR4 antagonist
|
GSK812397 is a potent, selective, noncompetitive, orally available antagonist of CXCR4 receptor, inhibits entry of X4-tropic strains of HIV-1 with IC50 of 4.60 nM and 1.50 nM in PBMCs and HOS assays, respectively. |
PC-35087 |
TIQ-15
CXCR4 antagonist
|
TIQ-15 is a potent and selective CXCR4 antagonist, inhibits attachment of X4 HIV-1IIIB virus in MAGI-CCR5/CXCR4 cells with IC50 of 3 nM. |
PC-35039 |
BI 639667
CCR1 inhibitor
|
BI 639667 (BI639667) is a potent and selective antagonist of human CCR1 with binding IC50 of 5.4 nM, inhibits chemotaxis with IC50 of 2.4 nM. |
PC-35036 |
BMS-817399
CCR1 inhibitor
|
BMS-817399 is a potent, selective, orally bioavailable CCR1 antagonist with binding IC50 of 1 nM, inhibits MIP-1α-induced chemotaxis with IC50 of 6 nM. |
PC-35030 |
BI 6901
CCR10 antagonist
|
BI 6901 is a potent, selective CCR10 antagonist with Aequorin Ca2+ flux pIC50 of 9.0, shows high selectivity over other GPCRs. |
PC-35029 |
CCR10 antagonist 1
|
CCR10 antagonist 1 is a potent, selective CCR10 antagonist with IC50 of 690 nM. |
PC-63566 |
BMS-457
CCR1 inhibitor
|
BMS-457 is a potent and selective CCR1 antagonist with binding IC50 of 0.8 nM, >1,000-fold selectivity against other CC family receptors. |
PC-63440 |
R243
|
R243 is a potent, small molecule CCR8 antagonist that inhibits CCR8 signaling and chemotaxis, inhibits CCL1-induced Ca2+ flux and CCL1-driven peritoneal macrophages aggregation at 0.2 uM. |
PC-42889 |
BX471
CCR1 inhibitor
|
BX471 is a potent, selective, non-peptide CCR1 antagonist with Ki of 1 nM for hCCR1, displays 100 times less affinity for rat CCR1. |
PC-62989 |
Elubrixin
|
Elubrixin (SB-656933, GSK-656933) is a potent, selective, competitive and reversible CXCR2 antagonist. |
PC-62762 |
AZD-4818
CCR1 inhibitor
|
AZD-4818 is a highly potent, selective CCR1 antagonist with pIC50 of 8.6, inhibits chemotaxia of human monocytes to MIP-1α in a concentration-dependent manner. |
PC-62752 |
C-021
CCR4 antagonist
|
C-021 is a potent and orally bioavailable CCR4 antagonist with IC50 of 0.14 uM and 0.039 uM for inhibition of chemotaxis in human and mouse, respectively.. |