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Cat. No. Product Name Information
PC-35088

GSK812397

CXCR4 antagonist

GSK812397 is a potent, selective, noncompetitive, orally available antagonist of CXCR4 receptor, inhibits entry of X4-tropic strains of HIV-1 with IC50 of 4.60 nM and 1.50 nM in PBMCs and HOS assays, respectively.
PC-35087

TIQ-15

CXCR4 antagonist

TIQ-15 is a potent and selective CXCR4 antagonist, inhibits attachment of X4 HIV-1IIIB virus in MAGI-CCR5/CXCR4 cells with IC50 of 3 nM.
PC-35039

BI 639667

CCR1 inhibitor

BI 639667 (BI639667) is a potent and selective antagonist of human CCR1 with binding IC50 of 5.4 nM, inhibits chemotaxis with IC50 of 2.4 nM.
PC-35036

BMS-817399

CCR1 inhibitor

BMS-817399 is a potent, selective, orally bioavailable CCR1 antagonist with binding IC50 of 1 nM, inhibits MIP-1α-induced chemotaxis with IC50 of 6 nM.
PC-35030

BI 6901

CCR10 antagonist

BI 6901 is a potent, selective CCR10 antagonist with Aequorin Ca2+ flux pIC50 of 9.0, shows high selectivity over other GPCRs.
PC-35029

CCR10 antagonist 1

CCR10 antagonist 1 is a potent, selective CCR10 antagonist with IC50 of 690 nM.
PC-63566

BMS-457

CCR1 inhibitor

BMS-457 is a potent and selective CCR1 antagonist with binding IC50 of 0.8 nM, >1,000-fold selectivity against other CC family receptors.
PC-63440

R243

R243 is a potent, small molecule CCR8 antagonist that inhibits CCR8 signaling and chemotaxis, inhibits CCL1-induced Ca2+ flux and CCL1-driven peritoneal macrophages aggregation at 0.2 uM.
PC-42889

BX471

CCR1 inhibitor

BX471 is a potent, selective, non-peptide CCR1 antagonist with Ki of 1 nM for hCCR1, displays 100 times less affinity for rat CCR1.
PC-62989

Elubrixin

Elubrixin (SB-656933, GSK-656933) is a potent, selective, competitive and reversible CXCR2 antagonist.
PC-62762

AZD-4818

CCR1 inhibitor

AZD-4818 is a highly potent, selective CCR1 antagonist with pIC50 of 8.6, inhibits chemotaxia of human monocytes to MIP-1α in a concentration-dependent manner.
PC-62752

C-021

CCR4 antagonist

C-021 is a potent and orally bioavailable CCR4 antagonist with IC50 of 0.14 uM and 0.039 uM for inhibition of chemotaxis in human and mouse, respectively..

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