| Cat. No. |
Product Name |
Information |
| PC-21092 |
TAPI-1
ADAM17 inhibitor
|
TAPI-1 is a small molecule inhibitor of TNFalpha converting enzyme (TACE, ADAM7), blocks the shedding of several cell surface proteins. |
| PC-21091 |
TAPI-0
ADAM17 inhibitor
|
TAPI-0 is a potent, selective inhibitor of TNFalpha converting enzyme (TACE, ADAM7) with IC50 of 100 nM. |
| PC-20621 |
CID 3117694
ADAM10 inhibitor
|
CID 3117694 is a selective, non-competitive inhibitor of ADAM10 with IC50 of 1.1 uM, does not inhibit ADAM17. |
| PC-20588 |
ARP100
MMP2 inhibitor
|
ARP100 (ARP-100) is a potent, selective gelatinase A (MMP-2) inhibitor with IC50 of 12 nM, weakly inhibits MMP-9 (IC50=200 nM) and >300-fold selectivity over MMP1/3/7. |
| PC-20540 |
MMP408
MMP-12 inhibitor
|
MMP408 (MMP 408) is a potent, selective matrix metalloprotease 12 (MMP-12) inhibitor with IC50 of 2.0 nM (human MMP-12), 60-fold selectivity over MMP-13. |
| PC-20537 |
MMP-12 inhibitor 9
MMP-12 inhibitor
|
MMP-12 inhibitor 9 is a potent selective MMP-12 inhibitor with IC50 of 177 nM, displays anti-inflammatory activity in vitro and in vivo. |
| PC-38902 |
TP0556351
MMP2 inhibitor
|
TP0556351 is a highly potent, selective matrix metalloproteinase-2 (MMP2) inhibitor with IC50 of 0.2 nM. |
| PC-73195 |
GI 254023X
ADAM10 inhibitor
|
GI 254023X is a potent, preferential ADAM10 inhibitor with IC50 of 5.3 nM, also inhibits MMP9 (IC50=2.5 nM), preferentially blocking ADAM10 but not TACE. |
| PC-73156 |
GW280264X
ADAM10/17 inhibitor
|
GW280264X is a potent, dual ADAM10/TACE (ADAM17) metalloproteinases inhibitor with IC50 of 8.0 nM and 11.5 nM, respectively. |
