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Cat. No. Product Name Information
PC-38688

Zaloglanstat

mPGES-1 inhibitor

Zaloglanstat (ISC-27864, GRC-27864) is a potent, selective, non-opioid and orally active microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor, exhibits significant analgesic efficacy in preclinical models for osteoarthritis and inflammatory arthritis.
PC-36096

Pizuglanstat

TAS-205 (Pizuglanstat, TAS205) is a potent, specific hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with IC50 of 55.8 nM, does not inhibit LPGDS at 100 uM.
PC-36090

Crisdesalazine

Crisdesalazine (AAD-2004, AAD2004) is a derivative of aspirin that inhibits microsomal PGE(2) synthase-1 (mPGES-1) activity in response to both LPS-treated BV2 cell with IC50 of 230 nM and recombinant human mPGES-1 protein with IC50 of 249 nM in vitro.
PC-61406

LY3031207

mPGES-1 inhibitor

LY3031207 is a novel potent (IC50=910 ng/mL), highly selective microsomal prostaglandin E synthase 1 inhibitor (mPGES-1) for treatment of undisclosed indications.
PC-45791

Benzydamine hydrochloride

Benzydamine hydrochloride is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties for pain relief and anti-inflammatory treatment of inflammatory conditions.
PC-20721

PF-4693627

mPGES-1 inhibitor

PF-4693627 is a potent, selective and orally bioavailable mPGES-1 inhibitor with IC50 of 3 nM.
PC-20720

UT-11

mPGES-1 inhibitor

UT-11 is a potent microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor, inhibits PGE2 production from human SK-N-AS and murine BV2 cells induced by LPS with IC50 of 0.1 and 2.0 uM, respectively.
PC-20005

mPGES-1 inhibitor UK-4b

mPGES-1 inhibitor UK-4b is a potent, hgihly selective and orally bioavailable inhibitor of human and mouse mPGES-1 enzymes with IC50 of 33 and 157 nM, respectively, effectively decreases carrageenan-stimulated PGE2 over-production.
PC-49705

mPGES-1 inhibitor PBCH

PBCH is a selective small-molecule inhibitor of mPGES-1, which is potent and can effectively inhibit both human and rodent orthologs.
PC-49642

TAS-204

H-PGDS inhibitor

TAS-204 (TAS204) is a potent, specific hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, inhibits recombinant human H-PGDS with IC50 of 24.0 nM.
PC-49641

TAS-205 monohydrate

H-PGDS inhibitor

TAS-205 (Pizuglanstat, TAS205) is a potent, specific hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with IC50 of 55.8 nM, does not inhibit LPGDS at 100 uM.
PC-49640

TFC-007

H-PGDS inhibitor

TFC-007 (TFC007) is a potent, specific hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with IC50 of 83 nM.

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