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Cat. No. Product Name Information
PC-20934

WB737

STAT3 inhibitor

WB737 is a potent and selective STAT3 inhibitor, directly binds to the STAT3 Src homology 2 (SH2) domain with KD value of 1.34 nM.
PC-20634

IST5-002

Stat5a/b inhibitor

IST5-002 is a specific small molecule taregeting STAT5 SH2-domain, inhibits both Stat5a/b phosphorylation and dimerization, robustly inhibits transcriptional activity of Stat5a (IC50=1.5 μM) and Stat5b (IC50=3.5 μM) in PC-3 cells.
PC-20120

K1836

STAT3 inhibitor

K1836 is a small molecule Stattic analog inhibitor of STAT3 signalling.
PC-49462

WB436B

STAT3 inhibitor

WB436B is a potent and highly selective small molecule inhibitor of STAT3, specifically targets the STAT3-SH2 domain with KD value of 94.3 nM.
PC-49434

DR-1-55

STAT3 inhibitor

DR-1-55 (DR-155) is a selective STAT3 inhibitor that covalently modifies a cysteine in the SH2 domain of STAT3.
PC-49088

STX-0119

STAT3 inhibitor

STX-0119 is a specific small molecule STAT3 dimerization inhibitor, binds to STAT3-SH2 domain and inhibits STAT3 transcription in STAT3-dependent luciferase reporter gene assay in HeLa cells with IC50 of 74 uM.
PC-47064

ODZ10117

STAT3 inhibitor

ODZ10117 is a small molecule inhibitor of STAT3, effectively inhibits the level of tyrosine phosphorylated STAT3 in various cancer cell lines.
PC-38849

W1131

STAT3 inhibitor

W1131 is a potent and selective STAT3 inhibitor with Kd of 7.55 uM in surface plasmon resonance (SPR) assays, inhibits STAT3 Tyr705 phosphorylation, triggers ferroptosis and possesses potent anti-tumor effects both in vitro and in vivo.
PC-73189

WP1066

STAT3 inhibitor

WP1066 is a potent, cell-active STAT3 pathway inhibitor, inhibits human malignant glioma U87-MG and U373-MG cells in vitro with IC50 of 5.6 and 3.7 uM.
PC-72849

SS-4

STAT3 inhibitor

SS-4 is a highly selective small molecule inhibitor of STAT3 tyrosine phosphorylation that potently inhibits GBM tumorigenesis in vitro and in vivo.
PC-38322

Stafia-1 prodrug

STAT5a inhibitor

Stafia-1 prodrug is the cell-permeable prodrug of Stafia-1 (Cat. PC-38321), and is suitable for cell based assays, inhibits tyrosine phosphorylation of STAT5a with selectivity over STAT5b in cultured human leukemia cells.
PC-38321

Stafia-1

STAT5a inhibitor

Stafia-1 is a selective inhibitor of STAT5a with Ki of 10.9 uM, preferentially inhibits STAT5a over the close homologue STAT5b (>9-fold) and other STAT family member.

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