| Cat. No. |
Product Name |
Information |
| PC-63154 |
AZD-1305
|
AZD-1305 is a novel antiarrhythmic agent that predominantly blocks the rapid component of IKr, the L-type calcium current, and the inward sodium current in mammalian cells and ventricular cardiomyocytes. |
| PC-62718 |
GS 462808
|
GS 462808 is a potent Late INa current inhibitor with IC50 of 1.33 uM. |
| PC-62647 |
Diminazene aceturate
|
Diminazene aceturate is an anti-infective agent, also is a slow pore blocker of acid-sensing ion channel 1a (ASIC1a) with IC50 of 0.3 uM. |
| PC-61870 |
PF-04531083
|
PF-04531083 (PF 4531083) is a potent and selective, orally available sodium channel Nav1.8 blocker for treatment of pain. . |
| PC-61857 |
PF-05241328
|
PF-05241328 (PF 5241328) is a potent and selective, orally active inhibitor of voltage-dependent sodium channel Nav1.7 for treatment of neuropathic pain.. |
| PC-61854 |
AZD-3161
|
AZD-3161 is a potent and selective sodium channel Nav1.7 blocker for treatment of nociceptive pain. . |
| PC-61853 |
PF-04856264
|
PF-04856264 is a potent, selective Nav1.7 blocker with IC50 of 28 nM, dispalys >1,000-fold selectivity over Nav1.5. |
| PC-61336 |
Lacosamide
|
An anticonvulsant compound that enhances the slow inactivation of voltage-gated sodium channels without affecting the fast inactivation of voltage-gated sodium channels. |
| PC-47508 |
Benzocaine
|
Benzocaine is a local anesthetic. |
| PC-45927 |
Proparacaine hydrochloride
|
An irreversible local anesthetic. |
| PC-45625 |
Nav1.7-IN-2
|
An inhibitor of voltage-gated sodium channel Nav1.7 (IC50=80 nM). |
| PC-45224 |
Ranolazine dihydrochloride
|
An anti-ischemic agent that has been shown to inhibit late I(Na) and I(Kr) and to have antiarrhythmic effects in various preclinical in vitro models. |
