| Cat. No. |
Product Name |
Information |
| PC-20055 |
BI-9267
NHE1/SLC9A1 inhibitor
|
BI-9267 is a potent, selective antagonist of the sodium-hydrogen antiporter 1 (NHE1, SLC9A1). |
| PC-49611 |
A-887826
Nav 1.8 blocker
|
A-887826 (A 887826) is a potent and voltage-dependent Na(v)1.8 sodium channel blocker with IC50 of 11 nM (hNav1.8), potently blocks tetrodotoxin-resistant sodium (TTX-R Na(+)) currents (IC50=8 nM) from small diameter rat DRG neurons. |
| PC-47037 |
QX-314 bromide
|
QX 314 bromide is a membrane impermeable quaternary derivative of lidocaine, a blocker of voltage-activated Na+ channels, also inhibits calcium currents in hippocampal CA1 pyramidal neurons. |
| PC-47030 |
BW-031 iodide
Nav1.7 inhibitor
|
BW-031 iodide is a potent cationic sodium channel inhibitor, inhibited Nav 1.7 (IC50=9.5 uM) and Nav 1.1 channels with approximately sixfold greater potency than QX-314. |
| PC-47029 |
BW-031 chloride
Nav1.7 inhibitor
|
BW-031 chloride is a potent cationic sodium channel inhibitor, inhibited Nav 1.7 (IC50=9.5 uM) and Nav 1.1 channels with approximately sixfold greater potency than QX-314. |
| PC-38569 |
DPI 201-106
Na+ channel opener
|
DPI 201-106 (SDZ 201106) is a positive inotropic agent that prolongs the open state of cardiac voltage-gated Na+ channels. |
| PC-38398 |
Idrevloride
ENaC inhibitor
|
Idrevloride is a potent, selective epithelial sodium channel (ENaC) blocker with potential for the treatment of skin disorders. |
| PC-73408 |
Bliretrigine
Sodium Channel inhibitor
|
Bliretrigine is a sodium channel blocker with the effect of relieving pain. |
| PC-73335 |
ASIC1a inhibitor 5b
ASIC1a inhibitor
|
ASIC1a inhibitor 5b is a highly selective and potent ASIC1a inhibitor, inhibits proton-evoked ASIC1a currents with an apparent IC50 of 27 nM at pH 6.7. |
| PC-73334 |
Psalmotoxin 1
ASIC1a inhibitor
|
Psalmotoxin 1 (PCTX1) is a potent and selective acid-sensing ion channel 1a (ASIC1a) blocker with IC50 of 0.9 nM. |
| PC-72811 |
NaV1.7 inhibitor Compound 194
NaV1.7 inhibitor
|
NaV1.7 inhibitor Compound 194 is a potent and selective inhibitor of NaV1.7 currents in DRG neurons via inhibition of the CRMP2-Ubc9 interaction. |
| PC-72209 |
SSCI-2
Nav1.7 inhibitor
|
SSCI-2 is a highly potent, selective NaV1.7 inhibitor with IC50 of 9 and 17 nM on human and rhesus Nav1.7 channels, respectively. |
