| Cat. No. |
Product Name |
Information |
| PC-70213 |
Flecainide
|
A class Ic antiarrhythmic agent used to prevent and treat tachyarrhythmias, works by blocking the Nav1.5 sodium channel in the heart, slowing the upstroke of the cardiac action potential. |
| PC-60194 |
AnCoA4
Orai1 channel inhibitor
|
AnCoA4 (AnCoA-4, Jamaicin) is a potent Orai1 channel inhibitor that inhibits store-operated calcium (SOC) with EC50 of 0.88 uM. |
| PC-60005 |
A-317567
|
A-317567 (A317567) is a novel potent acid sensing ion channel (ASIC) blocker with IC50 of 2-30 uM. |
| PC-42621 |
PH-064
|
PH-064 (BIM-46187) is an inhibitor of heterotrimeric G-protein complex. |
| PC-45079 |
ICA-121431
Nav1.3/Nav1.1 inhibitor
|
A potent, selective small molecule human Nav1.3/Nav1.1 channel inhibitor with IC50 of 19 nM. |
| PC-21839 |
S3969
ENaC activator
|
S3969 is a small molecule activator of the human epithelial sodium channel (ENaC) with EC50 of 1.2 uM in ENaC-expressing oocytes. |
| PC-21779 |
XPC-5462
NaV1.2/1.6 inhibitor
|
XPC-5462 is a potent, selective dual inhibitor of NaV1.6 and NaV1.2 with IC50 of 10.9 nM and 10.3 nM, respectively. |
| PC-21778 |
XPC-7224
NaV1.6 inhibitor
|
XPC-7224 is a potent, selective NaV1.6 inhibitor with IC50 of 78 nM and 130 nM for human and mouse NaV1.6, respectively, interacts with the inactivated state of the channel. |
| PC-21711 |
UTX-143
NHE5 inhibitor
|
UTX-143 is a potent, selective sodium-hydrogen exchange subtype 5 (NHE5) inhibitor with IC50 of 3.11 uM, 80-fold selective over NHE1. |
| PC-21678 |
LTGO-33
NaV1.8 inhibitor
|
LTGO-33 is a potent, selective inhibitor of voltage-gated sodium channel NaV1.8 with IC50 of 44 nM (hNaV1.8), 600-fold selectivity against NaV1.1-NaV1.7 and NaV1.9. |
| PC-21230 |
Aneratrigine
Sodium Channel inhibitor
|
Aneratrigine is a sodium channel protein type 9 subunit alpha blocker. |
| PC-20850 |
DS43260857
NaV1.7 inhibitor
|
DS43260857 is a potent, selective NaV1.7 inhibitor with IC50 of 15 nM (hNaV1.7), shows 440-fold and 930-fold selectivity over hNaV1.1 and hNaV1.5, respectively. |
