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Cat. No. Product Name Information
PC-62980

CMP-5 hydrochloride

CMP-5 (PRMT5-IN-5)is a first-in-class, small-molecule PRMT5-specific inhibitor that blocks EBV-driven B-lymphocyte transformation and survival, without effect on normal B cells.
PC-62484

MI-2-2 hydrochloride

MI-2-2 hydrochloride is a potent inhibitor of the menin-MLL interaction that binds to menin with low nanomolar affinity (Kd=22 nM).
PC-62468

EZH2-IN-3

EZH2-IN-3 is a highly selective small molecule inhibitor of EZH2 and EZH1 with IC50 of 21/197/213 nM for wt EZH2/EZH2 Y641N/wt EZH1 respectively.
PC-62408

Sinefungin

Sinefungin (A 9145.
PC-62310

A-395N

A-395N is the negative control compound of A-395, which is a potent, selective, and cellularly active PRC2 subunit EED inhibitor with Kd of 1.5 nM..
PC-70002

MIV-6R

A potent, ligand-efficient, and cell-active inhibitor menin-MLL interaction with IC50 of 56 nM, Kd of 85 nM.
PC-45679

XY1

XY1 is the inactive control compound of SGC-707.
PC-45465

UNC-1079

The piperidine analog of UNC1021.
PC-42113

MS-049

A potent, selective, and cell-active dual inhibitor of PRMT4 and PRMT6 with IC50 of 34±10 nM and 43±7 nM, respectively.
PC-42272

UNC3866

A potent, selective PRC1 chromodomains antagonist that binds to CBX4 and CBX7 with Kd of 100 nM.
PC-42740

UNC0224

A potent, selective G9a/GLP inhibitor with IC50 of 57 nM and 58 nM CLOT biochemical assays.
PC-45617

WDR5-0103

A potent MLL1-WDR5 interaction inhibitor with IC50 of 26.4 nM in competitive binding assay.

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