Cat. No. |
Product Name |
Information |
PC-62484 |
MI-2-2 hydrochloride
|
MI-2-2 hydrochloride is a potent inhibitor of the menin-MLL interaction that binds to menin with low nanomolar affinity (Kd=22 nM). |
PC-62468 |
EZH2-IN-3
|
EZH2-IN-3 is a highly selective small molecule inhibitor of EZH2 and EZH1 with IC50 of 21/197/213 nM for wt EZH2/EZH2 Y641N/wt EZH1 respectively. |
PC-62408 |
Sinefungin
|
Sinefungin (A 9145. |
PC-62310 |
A-395N
|
A-395N is the negative control compound of A-395, which is a potent, selective, and cellularly active PRC2 subunit EED inhibitor with Kd of 1.5 nM.. |
PC-70002 |
MIV-6R
|
A potent, ligand-efficient, and cell-active inhibitor menin-MLL interaction with IC50 of 56 nM, Kd of 85 nM. |
PC-45679 |
XY1
|
XY1 is the inactive control compound of SGC-707. |
PC-45465 |
UNC-1079
|
The piperidine analog of UNC1021. |
PC-42272 |
UNC3866
|
A potent, selective PRC1 chromodomains antagonist that binds to CBX4 and CBX7 with Kd of 100 nM. |
PC-42740 |
UNC0224
|
A potent, selective G9a/GLP inhibitor with IC50 of 57 nM and 58 nM CLOT biochemical assays. |
PC-45617 |
WDR5-0103
|
A potent MLL1-WDR5 interaction inhibitor with IC50 of 26.4 nM in competitive binding assay. |
PC-45602 |
MI-136
|
A potent Menin-MLL interaction inhibitor with IC50 of 31 nM. |
PC-44607 |
UNC1215
|
A potent and selective chemical probe for the methyllysine (Kme) reading function of L3MBTL3 with Kd of 120 nM. |