| Cat. No. |
Product Name |
Information |
| PC-46014 |
Tadalafil
PDE5 inhibitor
|
Tadalafil (IC-351, IC351) is a potent, selective phosphodiesterase-5 (PDE5) inhibitor (IC50=1 nM). |
| PC-46013 |
Nortadalafil
PDE5 inhibitor
|
Nortadalafil (Demethyl Tadalafil) is demethyl tadalafil, a PDE5 inhibitor, currently marketed in pill form for treating erectile dysfunction (ED).. |
| PC-42219 |
Roflumilast Impurity E
PDE4 inhibitor
|
Roflumilast Impurity E (3-O-Decyclopropyl Roflumilast) is an impurity of Roflumilast, which is a selective and long-acting inhibitor of PDE-4 with IC50 value of 0.8 nM. |
| PC-45282 |
Cilostazol
PDE3 inhibitor
|
Cilostazol (OPC 13013, OPC 21) is a potent, selective inhibitor of PDE3A with IC50 of 0.2 uM. |
| PC-42698 |
Cilomilast
PDE4 inhibitor
|
Cilomilast (SB207499) is a potent and selective PDE4 inhibitor with IC50 of 95/120 nM for LPDE4/HPDE4. |
| PC-45821 |
PF-2545920
PDE10A inhibitor
|
PF-2545920 (Mardepodect) is a potent and selective PDE10A inhibitor with IC50 of 0.37 nM. |
| PC-22040 |
YM976
PDE4 inhibitor
|
YM976 is a potent, selective phosphodiesterase type 4 (PDE4) inhibitor with IC50 of 2.2 nM against PDE4 purified from human peripheral leukocytes. |
| PC-22039 |
BAY 60-7550
PDE2 inhibitor
|
BAY 60-7550 (Bay60-7550) is a potent and selective PDE2 inhibitor with Ki of 3.8 nM, IC50 of 4.7 nM (human PDE2A), and 2.0 nM (bovine purified PDE2). |
| PC-22038 |
CT-2450
PDE4 inhibitor
|
CT-2450 is a potent, selective phosphodiesterase (PDE IV, PDE4) inhibitor. |
| PC-21899 |
Anagrelide hydrochloride
PDE3 inhibitor
|
Anagrelide hydrochloride (BL4162A) is a potent inhibitor of phosphodiesterase type III (PDE3) with IC50 of 36 nM, inhibits platelet aggregation and bone marrow megakaryocytopoiesis. |
| PC-21518 |
D159687
PDE4D inhibitor
|
D159687 is a selective, negative allosteric modulator (inhibitor) of PDE4D with IC50 of 1.9 nM, >1,000 time more selective against PDE4 compared with other PDEs. |
| PC-21517 |
PDE4B inhibitor A-33
PDE4B inhibitor
|
PDE4B inhibitor A-33 is a potent, selective inhibitor of PDE4B with IC50 of 15 nM, >100-fold selective over PDE4D. |
