| Cat. No. |
Product Name |
Information |
| PC-38729 |
SHR1032
STING agonist
|
SHR1032 is a novel small molecule non-cyclic di-nucleotide STING agonist, exhibits significantly high affinity binding to STING and cellular reporter assay (EC50=30 nM). |
| PC-73371 |
MSA-2
STING agonist
|
MSA-2 is a potent and orally available non-nucleotide STING agonist with EC50 of 8.3 and 24 uM for human STING isoforms WT and HAQ, respectively. |
| PC-73368 |
STING activator Compound 53
STING agonist
|
STING activator Compound 53 is a potent small molecule activator of human STING with functional EC50 of 183 nM in immortalised and primary cells. |
| PC-73361 |
G150
cGAS inhibitor
|
G150 is a potent, specific human cyclic GMP-AMP synthase (cGAS) small-molecule inhibitor with IC50 of 10.2 nM, shows no inhibition against m-cGAS. |
| PC-73024 |
STING agonist BNBC
STING agonist
|
STING agonist BNBC (BNBC) is a human STING specific agonist that activates cGAS-STING pathway in a functional human STING-dependent manner. |
| PC-72369 |
MK-1454
STING agonist
|
MK-1454 (Ulevostinag) is a novel cyclic dinucleotide STING agonist with robust tumor cytokine upregulation and effective antitumor activity. |
| PC-38104 |
DUN99845
STING antagonist
|
DUN99845 (SN-001) is a STING inhbitor and inhibits the activation of the STING signal pathway. |
| PC-38087 |
SR-717
STING agonist
|
SR-717 (SR717) is a non-nucleotide, small-molecule STING agonist, demonstrates broad interspecies and interallelic specificity with EC50 of 2.1 uM and 2.2 uM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines. |
| PC-38078 |
SN-011
STING antagonist
|
SN-011 (SN011) is a potent, selective STING antagonist with IC50 of 76 nM (STING signaling inhibition). |
| PC-36011 |
STING inhibitor 18
STING inhibitor
|
STING inhibitor 18 is a novel cGAMP competitive ligand (antagonist) of the inactive form of STING with IC50 of 68 nM in the HAQ STING cGAMP displacement assays. |
| PC-35785 |
STING agonist diABZI compound 3
STING agonist
|
STING agonist diABZI compound 3 is an amidobenzimidazole (ABZI)-based compound that functions as a potent, specific, non-nucleotide STING agonist, induces dose-dependent activation of STING and secretion of IFN-β with EC50 of 130 nM in human PBMCs. |
| PC-35784 |
STING agonist diABZI compound 3 freebase
|
STING agonist diABZI compound 3 is an amidobenzimidazole (ABZI)-based compound that functions as a potent, specific, non-nucleotide STING agonist, induces dose-dependent activation of STING and secretion of IFN-β with EC50 of 130 nM in human PBMCs. |
